Metformin ameliorates HMGB1-mediated oxidative stress through mTOR pathway in experimental periodontitis

Metformin ameliorates HMGB1-mediated oxidative stress through mTOR pathway in experimental periodontitis

Periodontitis is an oral chronic inflammatory disease. Inhibiting tissue destruction and promoting tissue regeneration are important means for the treatment of periodontitis. Metformin not only has hypoglycemic effect but also has anti-inflammatory effect. Metformin has been shown to inhibit oxidati...

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Bibliographic Details
Main Authors:	Boyang Sun, Siqi Ying, Qian Ma, Han Li, Jie Li, Jinlin Song
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2023-03-01
Series:	Genes and Diseases
Subjects:	Autophagy Metformin Oxidative stress Periodontal ligament cells Periodontitis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352304221000830

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