Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study
Background: Tuberculosis is a major public health problem throughout the world particularly in resource limited countries. Measuring and reporting of TB treatment outcomes and identifying associated factors are fundamental part of TB treatment. The aim of this study was to assess TB treatment outcom...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-04-01
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| Series: | Journal of Public Health Research |
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| Online Access: | https://www.jphres.org/index.php/jphres/article/view/2046 |
| _version_ | 1797965476551196672 |
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| author | Melese Yeshambaw Teferi Lukas Dingato Didana Tsegaye Hailu Simon Genet Woldesenbet Senedu Bekele Adane Mihret |
| author_facet | Melese Yeshambaw Teferi Lukas Dingato Didana Tsegaye Hailu Simon Genet Woldesenbet Senedu Bekele Adane Mihret |
| author_sort | Melese Yeshambaw Teferi |
| collection | DOAJ |
| description | Background: Tuberculosis is a major public health problem throughout the world particularly in resource limited countries. Measuring and reporting of TB treatment outcomes and identifying associated factors are fundamental part of TB treatment. The aim of this study was to assess TB treatment outcome and associated factors among TB patients in Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia.
Design and Methods: Facility based retrospective cohort study was conducted in Wolayta Sodo Teaching and Referral Hospital. All TB patients who registered during September 2014 to August 2019 and had known treatment outcome were included in the study. The data were collected using pretested structured data extraction format that included demographic, clinical and treatment outcome variables. SPSS Version 23 for windows was used for data processing. Bivariate and multivariate analysis with 95% confidence interval (CI) was employed to infer associations between the independent and dependent variables.
Results: Of total 232 TB patient included in the study, 54.3% were male,80.2% were urban residents, 65.9% were pulmonary TB (PTB). From the total 153 PTB cases,31.5% were smear positive, 17.2% were HIV co-infected and all of them were on antiretroviral treatment. Most, 97.0% of the TB cases were newly diagnosed and all were treated as first line treatment category. The overall treatment success rate was 82.5% (28% cured 54.3% completed), 11.2% loss to follow-up, 4.7% dead and 0.9% treatment failure. The treatment success rate of HIV co-infected TB patients was 77.5%. There was no significant association between TB treatment outcome and age, sex, residence, type of TB, category of patients and HIV status.
Conclusions: The treatment success rate was low (82.5%) which is below the90% threshold defined standard with high proportion of patient’s lost to follow-up (11.2%). A higher number of transfer-out cases were recorded in this study. Thus, supervision and monitoring of DOTs implementation, improved counseling service, mechanisms for lost to follow-up patients should be strengthen. Establish efficient referral and contact tracing mechanisms for transferred-out cases and document their treatment outcomes of status is also fundamental. |
| first_indexed | 2024-04-11T02:00:33Z |
| format | Article |
| id | doaj.art-4ba56a5511134c92814c023250d479d0 |
| institution | Directory Open Access Journal |
| issn | 2279-9028 2279-9036 |
| language | English |
| last_indexed | 2024-04-11T02:00:33Z |
| publishDate | 2021-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Public Health Research |
| spelling | doaj.art-4ba56a5511134c92814c023250d479d02023-01-03T04:11:33ZengSAGE PublishingJournal of Public Health Research2279-90282279-90362021-04-0110.4081/jphr.2021.2046Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective studyMelese Yeshambaw Teferi0Lukas Dingato Didana1Tsegaye Hailu2Simon Genet Woldesenbet3Senedu Bekele4Adane Mihret5Armauer Hansen Research Institute (AHRI), Addis AbabaWolayta Sodo University Teaching and Referral HospitalArmauer Hansen Research Institute (AHRI), Addis AbabaArmauer Hansen Research Institute (AHRI), Addis AbabaArmauer Hansen Research Institute (AHRI), Addis AbabaArmauer Hansen Research Institute (AHRI), Addis AbabaBackground: Tuberculosis is a major public health problem throughout the world particularly in resource limited countries. Measuring and reporting of TB treatment outcomes and identifying associated factors are fundamental part of TB treatment. The aim of this study was to assess TB treatment outcome and associated factors among TB patients in Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia. Design and Methods: Facility based retrospective cohort study was conducted in Wolayta Sodo Teaching and Referral Hospital. All TB patients who registered during September 2014 to August 2019 and had known treatment outcome were included in the study. The data were collected using pretested structured data extraction format that included demographic, clinical and treatment outcome variables. SPSS Version 23 for windows was used for data processing. Bivariate and multivariate analysis with 95% confidence interval (CI) was employed to infer associations between the independent and dependent variables. Results: Of total 232 TB patient included in the study, 54.3% were male,80.2% were urban residents, 65.9% were pulmonary TB (PTB). From the total 153 PTB cases,31.5% were smear positive, 17.2% were HIV co-infected and all of them were on antiretroviral treatment. Most, 97.0% of the TB cases were newly diagnosed and all were treated as first line treatment category. The overall treatment success rate was 82.5% (28% cured 54.3% completed), 11.2% loss to follow-up, 4.7% dead and 0.9% treatment failure. The treatment success rate of HIV co-infected TB patients was 77.5%. There was no significant association between TB treatment outcome and age, sex, residence, type of TB, category of patients and HIV status. Conclusions: The treatment success rate was low (82.5%) which is below the90% threshold defined standard with high proportion of patient’s lost to follow-up (11.2%). A higher number of transfer-out cases were recorded in this study. Thus, supervision and monitoring of DOTs implementation, improved counseling service, mechanisms for lost to follow-up patients should be strengthen. Establish efficient referral and contact tracing mechanisms for transferred-out cases and document their treatment outcomes of status is also fundamental.https://www.jphres.org/index.php/jphres/article/view/2046Tuberculosistreatment outcomefactorsEthiopia |
| spellingShingle | Melese Yeshambaw Teferi Lukas Dingato Didana Tsegaye Hailu Simon Genet Woldesenbet Senedu Bekele Adane Mihret Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study Journal of Public Health Research Tuberculosis treatment outcome factors Ethiopia |
| title | Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study |
| title_full | Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study |
| title_fullStr | Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study |
| title_full_unstemmed | Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study |
| title_short | Tuberculosis treatment outcome and associated factors among tuberculosis patients at Wolayta Sodo Teaching and Referral Hospital, Southern Ethiopia: a retrospective study |
| title_sort | tuberculosis treatment outcome and associated factors among tuberculosis patients at wolayta sodo teaching and referral hospital southern ethiopia a retrospective study |
| topic | Tuberculosis treatment outcome factors Ethiopia |
| url | https://www.jphres.org/index.php/jphres/article/view/2046 |
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