SMAD Proteins in TGF-β Signalling Pathway in Cancer: Regulatory Mechanisms and Clinical Applications

SMAD Proteins in TGF-β Signalling Pathway in Cancer: Regulatory Mechanisms and Clinical Applications

Suppressor of mother against decapentaplegic (SMAD) family proteins are central to one of the most versatile cytokine signalling pathways in metazoan biology, the transforming growth factor-β (TGF-β) pathway. The TGF-β pathway is widely known for its dual role in cancer progression as both an inhibi...

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Bibliographic Details
Main Authors: Qi Wang, Fei Xiong, Guanhua Wu, Da Wang, Wenzheng Liu, Junsheng Chen, Yongqiang Qi, Bing Wang, Yongjun Chen
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Diagnostics
Subjects:
SMAD
transforming growth factor-β
cancer
diagnosis
treatment
Online Access:https://www.mdpi.com/2075-4418/13/17/2769

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