Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
<h4>Background</h4>Many studies have considered the prevalence of dementia in mainland China, Hong Kong and Taiwan. However, area level estimates have not been produced. This study examines area differences across mainland China, Hong Kong and Taiwan adjusting for the effect of methodolo...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776645/pdf/?tool=EBI |
| _version_ | 1818337717172305920 |
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| author | Yu-Tzu Wu Hsin-Yi Lee Samuel Norton Chuanfeng Chen Hongxia Chen Chenglin He Jane Fleming Fiona E Matthews Carol Brayne |
| author_facet | Yu-Tzu Wu Hsin-Yi Lee Samuel Norton Chuanfeng Chen Hongxia Chen Chenglin He Jane Fleming Fiona E Matthews Carol Brayne |
| author_sort | Yu-Tzu Wu |
| collection | DOAJ |
| description | <h4>Background</h4>Many studies have considered the prevalence of dementia in mainland China, Hong Kong and Taiwan. However, area level estimates have not been produced. This study examines area differences across mainland China, Hong Kong and Taiwan adjusting for the effect of methodological factors with the aim of producing estimates of the numbers of people with dementia in these areas.<h4>Method and findings</h4>A search of Chinese and English databases identified 76 dementia prevalence studies based on samples drawn from mainland China, Hong Kong and Taiwan between 1980 and 2012. A pattern of significantly decreasing prevalence was observed from northern, central, southern areas of mainland China, Hong Kong and Taiwan. Area variations in dementia prevalence were not explained by differences in methodological factors (diagnostic criteria, age range, study sample size and sampling method), socioeconomic level or life expectancy between areas. The results of meta-analysis were applied to current population data to provide best estimate. Based on the DSM-IV diagnostic criteria, the total number of people aged 60 and over with dementia in mainland China, Hong Kong and Taiwan is 8.4 million (4.6%, 95% CI: 3.4, 5.8) and in northern, central and southern areas are 3.8 (5.1%, 95% CI: 4.1, 6.1), 3.2 (4.4%, 95% CI: 3.2, 5.6) and 1.2 (3.9%, 95% CI: 2.3, 5.4) million respectively. These estimates were mainly based on the studies existing in highly developed areas and potentially affected by incomplete and insufficient data.<h4>Conclusions</h4>The findings of this review provide a robust estimate of area differences in dementia prevalence. Application of the estimated prevalence to population data reveals the number of people with dementia is expected to double every 20 years, areas in mainland China will be facing the greatest dementia challenge. |
| first_indexed | 2024-12-13T14:59:39Z |
| format | Article |
| id | doaj.art-4ba8f185e27f4f81aaa9d945856b9e28 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T14:59:39Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-4ba8f185e27f4f81aaa9d945856b9e282022-12-21T23:41:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0186e6625210.1371/journal.pone.0066252Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.Yu-Tzu WuHsin-Yi LeeSamuel NortonChuanfeng ChenHongxia ChenChenglin HeJane FlemingFiona E MatthewsCarol Brayne<h4>Background</h4>Many studies have considered the prevalence of dementia in mainland China, Hong Kong and Taiwan. However, area level estimates have not been produced. This study examines area differences across mainland China, Hong Kong and Taiwan adjusting for the effect of methodological factors with the aim of producing estimates of the numbers of people with dementia in these areas.<h4>Method and findings</h4>A search of Chinese and English databases identified 76 dementia prevalence studies based on samples drawn from mainland China, Hong Kong and Taiwan between 1980 and 2012. A pattern of significantly decreasing prevalence was observed from northern, central, southern areas of mainland China, Hong Kong and Taiwan. Area variations in dementia prevalence were not explained by differences in methodological factors (diagnostic criteria, age range, study sample size and sampling method), socioeconomic level or life expectancy between areas. The results of meta-analysis were applied to current population data to provide best estimate. Based on the DSM-IV diagnostic criteria, the total number of people aged 60 and over with dementia in mainland China, Hong Kong and Taiwan is 8.4 million (4.6%, 95% CI: 3.4, 5.8) and in northern, central and southern areas are 3.8 (5.1%, 95% CI: 4.1, 6.1), 3.2 (4.4%, 95% CI: 3.2, 5.6) and 1.2 (3.9%, 95% CI: 2.3, 5.4) million respectively. These estimates were mainly based on the studies existing in highly developed areas and potentially affected by incomplete and insufficient data.<h4>Conclusions</h4>The findings of this review provide a robust estimate of area differences in dementia prevalence. Application of the estimated prevalence to population data reveals the number of people with dementia is expected to double every 20 years, areas in mainland China will be facing the greatest dementia challenge.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776645/pdf/?tool=EBI |
| spellingShingle | Yu-Tzu Wu Hsin-Yi Lee Samuel Norton Chuanfeng Chen Hongxia Chen Chenglin He Jane Fleming Fiona E Matthews Carol Brayne Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis. PLoS ONE |
| title | Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis. |
| title_full | Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis. |
| title_fullStr | Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis. |
| title_full_unstemmed | Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis. |
| title_short | Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis. |
| title_sort | prevalence studies of dementia in mainland china hong kong and taiwan a systematic review and meta analysis |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776645/pdf/?tool=EBI |
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