Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis

Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis

Thrombosis can cause localized ischemia and tissue hypoxia, and both of these are linked to cancer metastasis. Vascular micro-occlusion can occur as a result of arrest of circulating tumour cells in small capillaries, giving rise to microthrombotic events that affect flow, creating localized hypoxic...

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Bibliographic Details
Main Authors: Colin E. Evans, Asis Palazon, Jingwei Sim, Petros A. Tyrakis, Alice Prodger, Xiao Lu, Saria Chan, Pär-Ola Bendahl, Mattias Belting, Love Von Euler, Helene Rundqvist, Randall S. Johnson, Cristina Branco
Format: Article
Language:English
Published: The Company of Biologists 2017-05-01
Series:Biology Open
Subjects:
HIF
Hypoxia
Thrombosis
Metastasis
Microvascular
Online Access:http://bio.biologists.org/content/6/5/688

Internet

http://bio.biologists.org/content/6/5/688

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