Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (...
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| Format: | Article |
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MDPI AG
2023-05-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/11/1842 |
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| author | Germana de Nucci Tommaso Gabbani Giovanna Impellizzeri Simona Deiana Paolo Biancheri Laura Ottaviani Leonardo Frazzoni Enzo Domenico Mandelli Paola Soriani Maurizio Vecchi Gianpiero Manes Mauro Manno |
| author_facet | Germana de Nucci Tommaso Gabbani Giovanna Impellizzeri Simona Deiana Paolo Biancheri Laura Ottaviani Leonardo Frazzoni Enzo Domenico Mandelli Paola Soriani Maurizio Vecchi Gianpiero Manes Mauro Manno |
| author_sort | Germana de Nucci |
| collection | DOAJ |
| description | Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this setting is still controversial. The aim of this retrospective multicenter study was to evaluate the accuracy of L-EUS and CECT in preoperative GC staging, with regards to depth of tumor invasion (T staging) and nodal involvement (N staging). Materials and methods: 191 consecutive patients who underwent surgical resection for GC were retrospectively enrolled. Preoperative staging had been performed using both L-EUS and CECT, and the results were compared to postoperative staging by histopathologic analysis of surgical specimens. Results: L-EUS diagnostic accuracy for depth of invasion of the GC was 100%, 60%, 74%, and 80% for T1, T2, T3, and T4, respectively. CECT accuracy for T staging was 78%, 55%, 45%, and 10% for T1, T2, T3, and T4, respectively. L-EUS diagnostic accuracy for N staging of GC was 85%, significantly higher than CECT accuracy (61%). Conclusions: Our data suggest that L-EUS has a higher accuracy than CECT in preoperative T and N staging of GC. |
| first_indexed | 2024-03-11T03:09:26Z |
| format | Article |
| id | doaj.art-4bb506254c094de8a856fc2e852f5040 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T03:09:26Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-4bb506254c094de8a856fc2e852f50402023-11-18T07:41:52ZengMDPI AGDiagnostics2075-44182023-05-011311184210.3390/diagnostics13111842Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter StudyGermana de Nucci0Tommaso Gabbani1Giovanna Impellizzeri2Simona Deiana3Paolo Biancheri4Laura Ottaviani5Leonardo Frazzoni6Enzo Domenico Mandelli7Paola Soriani8Maurizio Vecchi9Gianpiero Manes10Mauro Manno11Gastroenterology and Digestive Endoscopy Unit, ASST Rhodense, 20094 Garbagnate Milanese, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyGastroenterology Unit, Surgical and Medical Sciences Department, Sant’Orsola Malpighi Hospital, 40138 Bologna, ItalyGastroenterology and Digestive Endoscopy Unit, ASST Rhodense, 20094 Garbagnate Milanese, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyGastroenterology Unit, Major Policlinic Hospital, 20122 Milan, ItalyGastroenterology and Digestive Endoscopy Unit, ASST Rhodense, 20094 Garbagnate Milanese, ItalyGastroenterology and Digestive Endoscopy Unit, Azienda USL Modena, 41012 Carpi, ItalyIntroduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this setting is still controversial. The aim of this retrospective multicenter study was to evaluate the accuracy of L-EUS and CECT in preoperative GC staging, with regards to depth of tumor invasion (T staging) and nodal involvement (N staging). Materials and methods: 191 consecutive patients who underwent surgical resection for GC were retrospectively enrolled. Preoperative staging had been performed using both L-EUS and CECT, and the results were compared to postoperative staging by histopathologic analysis of surgical specimens. Results: L-EUS diagnostic accuracy for depth of invasion of the GC was 100%, 60%, 74%, and 80% for T1, T2, T3, and T4, respectively. CECT accuracy for T staging was 78%, 55%, 45%, and 10% for T1, T2, T3, and T4, respectively. L-EUS diagnostic accuracy for N staging of GC was 85%, significantly higher than CECT accuracy (61%). Conclusions: Our data suggest that L-EUS has a higher accuracy than CECT in preoperative T and N staging of GC.https://www.mdpi.com/2075-4418/13/11/1842gastric cancer staginglinear endoscopic ultrasounddiagnostic accuracy |
| spellingShingle | Germana de Nucci Tommaso Gabbani Giovanna Impellizzeri Simona Deiana Paolo Biancheri Laura Ottaviani Leonardo Frazzoni Enzo Domenico Mandelli Paola Soriani Maurizio Vecchi Gianpiero Manes Mauro Manno Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study Diagnostics gastric cancer staging linear endoscopic ultrasound diagnostic accuracy |
| title | Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study |
| title_full | Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study |
| title_fullStr | Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study |
| title_full_unstemmed | Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study |
| title_short | Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study |
| title_sort | linear eus accuracy in preoperative staging of gastric cancer a retrospective multicenter study |
| topic | gastric cancer staging linear endoscopic ultrasound diagnostic accuracy |
| url | https://www.mdpi.com/2075-4418/13/11/1842 |
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