Effect of dexamethasone on osteoclast formation in the alveolar
This study was planned to determine whether a short period dexamethasone treatment induce alveolar bone loss or not, therefore, twenty six male albino rabbits were divided into three groups as follow: Test groups I (10 rabbits) received 1.56 mg/kg dexamethasone intraperitoneal injection daily for tw...
| Main Authors: | , |
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| Format: | Article |
| Language: | Arabic |
| Published: |
University of Mosul, College of Veterinary Medicine
2009-01-01
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| Series: | Iraqi Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://www.vetmedmosul.org/ijvs/media/9-1-3e.pdf |
| _version_ | 1818390319326035968 |
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| author | A. Y. Yasear S. A. Hamouda |
| author_facet | A. Y. Yasear S. A. Hamouda |
| author_sort | A. Y. Yasear |
| collection | DOAJ |
| description | This study was planned to determine whether a short period dexamethasone treatment induce alveolar bone loss or not, therefore, twenty six male albino rabbits were divided into three groups as follow: Test groups I (10 rabbits) received 1.56 mg/kg dexamethasone intraperitoneal injection daily for two weeks, test group II (10 rabbits) received 3.12 mg/kg dexamethasone intraperitoneal injection daily, and the control group (6 rabbits) received saline solution for same period. The animals were sacrificed and histological sections were prepared from the alveolar bone of molar areas of mandible, as well as morphometric analysis of osteoclasts number was performed. The results showed a significant increase in the number of osteoclasts, which indicates that bone loss, is quite inevitable secondary to dexamethasone treatment even in a short period of treatment for two weeks. |
| first_indexed | 2024-12-14T04:55:44Z |
| format | Article |
| id | doaj.art-4bb641bf1d2d4aa88cc44a0588842001 |
| institution | Directory Open Access Journal |
| issn | 1607-3894 2071-1255 |
| language | Arabic |
| last_indexed | 2024-12-14T04:55:44Z |
| publishDate | 2009-01-01 |
| publisher | University of Mosul, College of Veterinary Medicine |
| record_format | Article |
| series | Iraqi Journal of Veterinary Sciences |
| spelling | doaj.art-4bb641bf1d2d4aa88cc44a05888420012022-12-21T23:16:22ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552009-01-012311316Effect of dexamethasone on osteoclast formation in the alveolarA. Y. YasearS. A. HamoudaThis study was planned to determine whether a short period dexamethasone treatment induce alveolar bone loss or not, therefore, twenty six male albino rabbits were divided into three groups as follow: Test groups I (10 rabbits) received 1.56 mg/kg dexamethasone intraperitoneal injection daily for two weeks, test group II (10 rabbits) received 3.12 mg/kg dexamethasone intraperitoneal injection daily, and the control group (6 rabbits) received saline solution for same period. The animals were sacrificed and histological sections were prepared from the alveolar bone of molar areas of mandible, as well as morphometric analysis of osteoclasts number was performed. The results showed a significant increase in the number of osteoclasts, which indicates that bone loss, is quite inevitable secondary to dexamethasone treatment even in a short period of treatment for two weeks.http://www.vetmedmosul.org/ijvs/media/9-1-3e.pdfDexamethasoneAlveolar boneRabbit |
| spellingShingle | A. Y. Yasear S. A. Hamouda Effect of dexamethasone on osteoclast formation in the alveolar Iraqi Journal of Veterinary Sciences Dexamethasone Alveolar bone Rabbit |
| title | Effect of dexamethasone on osteoclast formation in the alveolar |
| title_full | Effect of dexamethasone on osteoclast formation in the alveolar |
| title_fullStr | Effect of dexamethasone on osteoclast formation in the alveolar |
| title_full_unstemmed | Effect of dexamethasone on osteoclast formation in the alveolar |
| title_short | Effect of dexamethasone on osteoclast formation in the alveolar |
| title_sort | effect of dexamethasone on osteoclast formation in the alveolar |
| topic | Dexamethasone Alveolar bone Rabbit |
| url | http://www.vetmedmosul.org/ijvs/media/9-1-3e.pdf |
| work_keys_str_mv | AT ayyasear effectofdexamethasoneonosteoclastformationinthealveolar AT sahamouda effectofdexamethasoneonosteoclastformationinthealveolar |