Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
Patients who survive cardiac arrest often develop severe neurological dysfunction due to the hypoxic brain injury and reperfusion induced cell death. Therapeutic hypothermia (TH) has become a standard therapy of cerebral protection following the successful return of spontaneous circulation in pati...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6491/14918_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Patients who survive cardiac arrest often develop severe neurological dysfunction due to the hypoxic brain injury and reperfusion induced
cell death. Therapeutic hypothermia (TH) has become a standard therapy of cerebral protection following the successful return of
spontaneous circulation in patients of out-of-hospital cardiac arrest, according to American heart association guidelines. This is a case
report of a 30-year-old patient who developed in-hospital cardiac arrest and was revived after prolonged cardiopulmonary resuscitation
(CPR) and also required primary angioplasty. TH was then established with local measures for 24 hours for cerebral protection. The
patient was gradually and successfully weaned off from ventilator with no neurological impairment. There is an increasing evidence of TH
and its protective mechanisms in patients with non-shockable arrest rhythms with particular emphasis on neurological outcomes. This
article emphasizes the role of TH in every successful CPR irrespective of the cardiac rhythm. |
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| ISSN: | 2249-782X 0973-709X |