Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature

Patients who survive cardiac arrest often develop severe neurological dysfunction due to the hypoxic brain injury and reperfusion induced cell death. Therapeutic hypothermia (TH) has become a standard therapy of cerebral protection following the successful return of spontaneous circulation in pati...

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Main Authors: Gautam Rawal, Sankalp Yadav, Nitin Garg
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-09-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6491/14918_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
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author Gautam Rawal
Sankalp Yadav
Nitin Garg
author_facet Gautam Rawal
Sankalp Yadav
Nitin Garg
author_sort Gautam Rawal
collection DOAJ
description Patients who survive cardiac arrest often develop severe neurological dysfunction due to the hypoxic brain injury and reperfusion induced cell death. Therapeutic hypothermia (TH) has become a standard therapy of cerebral protection following the successful return of spontaneous circulation in patients of out-of-hospital cardiac arrest, according to American heart association guidelines. This is a case report of a 30-year-old patient who developed in-hospital cardiac arrest and was revived after prolonged cardiopulmonary resuscitation (CPR) and also required primary angioplasty. TH was then established with local measures for 24 hours for cerebral protection. The patient was gradually and successfully weaned off from ventilator with no neurological impairment. There is an increasing evidence of TH and its protective mechanisms in patients with non-shockable arrest rhythms with particular emphasis on neurological outcomes. This article emphasizes the role of TH in every successful CPR irrespective of the cardiac rhythm.
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spelling doaj.art-4bbca717a2844cdc822009d2e43b27722022-12-22T01:16:44ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-09-0199OD01OD0210.7860/JCDR/2015/14918.6491Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of LiteratureGautam Rawal0Sankalp Yadav1Nitin Garg2Attending Consultant-Critical Care, Rockland Hospital, Qutab Institutional Area, New Delhi, India.General Duty Medical Officer-II, Chest Clinic, Moti Nagar, New Delhi, India.Senior Consultant and Head-Critical Care, Rockland Hospital, Qutab Institutional Area, New Delhi, India.Patients who survive cardiac arrest often develop severe neurological dysfunction due to the hypoxic brain injury and reperfusion induced cell death. Therapeutic hypothermia (TH) has become a standard therapy of cerebral protection following the successful return of spontaneous circulation in patients of out-of-hospital cardiac arrest, according to American heart association guidelines. This is a case report of a 30-year-old patient who developed in-hospital cardiac arrest and was revived after prolonged cardiopulmonary resuscitation (CPR) and also required primary angioplasty. TH was then established with local measures for 24 hours for cerebral protection. The patient was gradually and successfully weaned off from ventilator with no neurological impairment. There is an increasing evidence of TH and its protective mechanisms in patients with non-shockable arrest rhythms with particular emphasis on neurological outcomes. This article emphasizes the role of TH in every successful CPR irrespective of the cardiac rhythm.https://jcdr.net/articles/PDF/6491/14918_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdfasystolecardiopulmonary resuscitationneurological outcomereturn of spontaneous circulation
spellingShingle Gautam Rawal
Sankalp Yadav
Nitin Garg
Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
Journal of Clinical and Diagnostic Research
asystole
cardiopulmonary resuscitation
neurological outcome
return of spontaneous circulation
title Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
title_full Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
title_fullStr Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
title_full_unstemmed Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
title_short Therapeutic Hypothermia after Prolonged Cardiac Arrest: Case Report with Review of Literature
title_sort therapeutic hypothermia after prolonged cardiac arrest case report with review of literature
topic asystole
cardiopulmonary resuscitation
neurological outcome
return of spontaneous circulation
url https://jcdr.net/articles/PDF/6491/14918_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
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AT nitingarg therapeutichypothermiaafterprolongedcardiacarrestcasereportwithreviewofliterature