Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients
Background and objective: We aimed to investigate biochemical factors affecting coronary collateral circulation development in an elderly population aged 75 years and over. Material and methods: The study group consisted of patients with a prior coronary angiography for stable coronary artery di...
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| Format: | Article |
| Language: | English |
| Published: |
MRE Press
2021-08-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://article.imrpress.com/journal/JOMH/18/1/10.31083/jomh.2021.085/1875-6859-18-1-011.pdf |
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| author | Ertan Vuruskan Irfan Veysel Duzen Mehmet Kaplan Gokhan Altunbas Enes Alıc Fatma Yılmaz Coskun Murat Sucu |
| author_facet | Ertan Vuruskan Irfan Veysel Duzen Mehmet Kaplan Gokhan Altunbas Enes Alıc Fatma Yılmaz Coskun Murat Sucu |
| author_sort | Ertan Vuruskan |
| collection | DOAJ |
| description | Background and objective: We aimed to investigate biochemical factors
affecting coronary collateral circulation development in an elderly population
aged 75 years and over.
Material and methods: The study group consisted of patients with a
prior coronary angiography for stable coronary artery disease (CAD). Patients
with total occlusion of at least one vessel were included in the study. Enrolled
patients were divided into two groups, good collateral (GC; n = 73) and bad
collateral (BC; n = 55), in accordance with the Cohen-Rentop’s classification
system.
Results: In comparison to the GC group, bilirubin levels were
significantly lower (p < 0.001), and fasting plasma glucose (FPG)
levels were significantly higher in the BC group (p = 0.026).
Low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein
cholesterol (HDL-C) levels were significantly lower in the BC group when compared
to the GC group (p = 0.002 and p < 0.001, respectively).
Backward elimination stepwise logistic regression analysis identified bilirubin
and FPG as variables that strongly predicted the presence of a well-developed
coronary collateral circulation and a poorly developed coronary collateral
circulation, respectively.
Conclusion: Bilirubin and FPG were seemed as the most important factors
affecting coronary collateral circulation development in patients with stable CAD
who were older than 75 years. |
| first_indexed | 2024-03-08T06:37:11Z |
| format | Article |
| id | doaj.art-4bbdabc41617468b911c38ec2b2411da |
| institution | Directory Open Access Journal |
| issn | 1875-6859 |
| language | English |
| last_indexed | 2024-03-08T06:37:11Z |
| publishDate | 2021-08-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj.art-4bbdabc41617468b911c38ec2b2411da2024-02-03T09:44:58ZengMRE PressJournal of Men's Health1875-68592021-08-0118101110.31083/jomh.2021.085S1875-6867(21)00242-6Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patientsErtan Vuruskan0Irfan Veysel Duzen1Mehmet Kaplan2Gokhan Altunbas3Enes Alıc4Fatma Yılmaz Coskun5Murat Sucu6Department of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyDepartment of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyDepartment of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyDepartment of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyDepartment of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyDepartment of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyDepartment of Cardiology, Faculty of Medicine, Gaziantep University, 27000 Gaziantep, TurkeyBackground and objective: We aimed to investigate biochemical factors affecting coronary collateral circulation development in an elderly population aged 75 years and over. Material and methods: The study group consisted of patients with a prior coronary angiography for stable coronary artery disease (CAD). Patients with total occlusion of at least one vessel were included in the study. Enrolled patients were divided into two groups, good collateral (GC; n = 73) and bad collateral (BC; n = 55), in accordance with the Cohen-Rentop’s classification system. Results: In comparison to the GC group, bilirubin levels were significantly lower (p < 0.001), and fasting plasma glucose (FPG) levels were significantly higher in the BC group (p = 0.026). Low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels were significantly lower in the BC group when compared to the GC group (p = 0.002 and p < 0.001, respectively). Backward elimination stepwise logistic regression analysis identified bilirubin and FPG as variables that strongly predicted the presence of a well-developed coronary collateral circulation and a poorly developed coronary collateral circulation, respectively. Conclusion: Bilirubin and FPG were seemed as the most important factors affecting coronary collateral circulation development in patients with stable CAD who were older than 75 years.https://article.imrpress.com/journal/JOMH/18/1/10.31083/jomh.2021.085/1875-6859-18-1-011.pdfcollateralbilirubincoronary artery diseaseolder patients |
| spellingShingle | Ertan Vuruskan Irfan Veysel Duzen Mehmet Kaplan Gokhan Altunbas Enes Alıc Fatma Yılmaz Coskun Murat Sucu Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients Journal of Men's Health collateral bilirubin coronary artery disease older patients |
| title | Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients |
| title_full | Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients |
| title_fullStr | Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients |
| title_full_unstemmed | Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients |
| title_short | Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients |
| title_sort | total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients |
| topic | collateral bilirubin coronary artery disease older patients |
| url | https://article.imrpress.com/journal/JOMH/18/1/10.31083/jomh.2021.085/1875-6859-18-1-011.pdf |
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