Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden
The risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known. However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated. Few studies on this topic have failed to prove a significant increase in VTE in patients...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Greater Baltimore Medical Center
2019-05-01
|
| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20009666.2019.1601059 |
| _version_ | 1797971549163094016 |
|---|---|
| author | Soluny Jean |
| author_facet | Soluny Jean |
| author_sort | Soluny Jean |
| collection | DOAJ |
| description | The risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known. However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated. Few studies on this topic have failed to prove a significant increase in VTE in patients using POC, including patients with a medical condition associated with an increased risk of thrombosis. Therefore, no specific consideration is warranted when using a POC in healthy young females, regardless of an inherited thrombophilia. We present a case of a young woman who has Factor V Leiden (FVL), presenting with an isolated pulmonary embolism (PE) while using a progesterone containing intrauterine device (IUD). The risk of VTE in FVL carriers seems to outweigh the benefit of contraception even when using progestin-only contraception. Therefore, non-hormonal contraception, such as copper IUD, seems to be the only safe alternative for contraception in this population. Further studies are needed to elucidate this observation. Abbreviation: PE: pulmonary embolism; FVL: factor V Leiden; VTE: venous thromboembolism; POC: progestin only contraception; CBC: complete blood count; CMP: complete metabolic panel; ABG: arterial Blood gas; CTPA: CT pulmonary angiography |
| first_indexed | 2024-04-11T03:33:17Z |
| format | Article |
| id | doaj.art-4bc3766f09c94c4288f6abd2915239f2 |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T03:33:17Z |
| publishDate | 2019-05-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-4bc3766f09c94c4288f6abd2915239f22023-01-02T05:42:53ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662019-05-019326426610.1080/20009666.2019.16010591601059Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V LeidenSoluny Jean0Interfaith Medical CenterThe risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known. However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated. Few studies on this topic have failed to prove a significant increase in VTE in patients using POC, including patients with a medical condition associated with an increased risk of thrombosis. Therefore, no specific consideration is warranted when using a POC in healthy young females, regardless of an inherited thrombophilia. We present a case of a young woman who has Factor V Leiden (FVL), presenting with an isolated pulmonary embolism (PE) while using a progesterone containing intrauterine device (IUD). The risk of VTE in FVL carriers seems to outweigh the benefit of contraception even when using progestin-only contraception. Therefore, non-hormonal contraception, such as copper IUD, seems to be the only safe alternative for contraception in this population. Further studies are needed to elucidate this observation. Abbreviation: PE: pulmonary embolism; FVL: factor V Leiden; VTE: venous thromboembolism; POC: progestin only contraception; CBC: complete blood count; CMP: complete metabolic panel; ABG: arterial Blood gas; CTPA: CT pulmonary angiographyhttp://dx.doi.org/10.1080/20009666.2019.1601059Factor V Leidenpulmonary embolismprogestin-only contraceptioncopper IUDprogestin IUDvenous thromboembolism |
| spellingShingle | Soluny Jean Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden Journal of Community Hospital Internal Medicine Perspectives Factor V Leiden pulmonary embolism progestin-only contraception copper IUD progestin IUD venous thromboembolism |
| title | Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
| title_full | Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
| title_fullStr | Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
| title_full_unstemmed | Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
| title_short | Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden |
| title_sort | isolated pulmonary embolism in a patient with progestin intrauterine device and factor v leiden |
| topic | Factor V Leiden pulmonary embolism progestin-only contraception copper IUD progestin IUD venous thromboembolism |
| url | http://dx.doi.org/10.1080/20009666.2019.1601059 |
| work_keys_str_mv | AT solunyjean isolatedpulmonaryembolisminapatientwithprogestinintrauterinedeviceandfactorvleiden |