Associação dos polimorfismos dos genes TGF-beta1, CD14, IL-4, IL-4R e ADAM33 com a gravidade da asma em crianças e adolescentes Association of TGF-beta1, CD14, IL-4, IL-4R and ADAM33 gene polymorphisms with asthma severity in children and adolescents
OBJETIVO: Verificar, em uma amostra de pacientes com asma atópica persistente leve, moderada e grave, a associação entre os polimorfismos dos genes fator de crescimento transformante-beta1 (TGF-beta1) (C-509T e T869C), CD14 (C-159T), IL-4 (C-590T), IL-4R (ILe50Val) e ADAM33 (S_2) com a gravidade da...
Main Authors: | Isabel C. J. de Faria, Elisangela J. de Faria, Adyléia A. D. C. Toro, José Dirceu Ribeiro, Carmen Silvia Bertuzzo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-06-01
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Series: | Jornal de Pediatria |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572008000300004 |
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