Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres.

Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres.

The uncapping of telomeres induces a DNA damage response. In Schizosaccharomyces pombe, deletion of pot1+ causes telomere uncapping and rapid telomere resection, resulting in chromosome fusion. Using the nmt-pot1-aid strain, we previously reported that Pot1 shut-off causes telomere loss and chromoso...

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Bibliographic Details
Main Authors: Tomoko Nanbu, Luân C Nguyễn, Ahmed G K Habib, Naoya Hirata, Shinobu Ukimori, Daiki Tanaka, Kenta Masuda, Katsunori Takahashi, Masashi Yukawa, Eiko Tsuchiya, Masaru Ueno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605587?pdf=render

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