Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study
Introduction: Screening programs with the use of specific diagnostic tools in asymptomatic patients are useful in identifying suspicious oral lesions and aid in the early diagnosis of oral cancer. The objective of the present study was to compare the oral rub and rinse technique with the conventiona...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
| Series: | Journal of Orofacial Sciences |
| Subjects: | |
| Online Access: | http://www.jofs.in/article.asp?issn=0975-8844;year=2022;volume=14;issue=1;spage=62;epage=65;aulast=D’Cruz |
| _version_ | 1797998844543238144 |
|---|---|
| author | Audrey Madonna D’Cruz Pushparaja Shetty Urvashi Ashwin Shetty Vinayak Kamath Bola Vishnudas Dinesh Prabhu |
| author_facet | Audrey Madonna D’Cruz Pushparaja Shetty Urvashi Ashwin Shetty Vinayak Kamath Bola Vishnudas Dinesh Prabhu |
| author_sort | Audrey Madonna D’Cruz |
| collection | DOAJ |
| description | Introduction: Screening programs with the use of specific diagnostic tools in asymptomatic patients are useful in identifying suspicious oral lesions and aid in the early diagnosis of oral cancer. The objective of the present study was to compare the oral rub and rinse technique with the conventional exfoliative cytology in the screening of oral malignant and potentially malignant diseases. Materials and Methods: An oral cancer screening program was conducted in the Dakshina Kannada district of Karnataka, India. The oral rub and rinse technique was performed on patients who had red/white lesions in the oral mucosa followed by the conventional exfoliative cytology. Scalpel biopsy was performed to confirm for presence or absence of malignancy in cases wherever indicated. Descriptive statistics (frequency and percentage) were used in the present study. Results: A total of 848 subjects were screened for oral cancer and precancer. About 112 participants had premalignant/malignant lesions and biopsy was performed on 30 subjects. Of these, 27.7% were Class I smears, 39.3% were Class II smears, 22.3% were Class III smears, 4.5% were Class IV smears, and 6.2% were unsatisfactory using the conventional technique, whereas the oral rub and rinse technique showed 26.8% Class I smears, 42.9% Class II smears, 19.6% Class III smears, 6.2% Class IV smears, 0.9% Class V smears, and 3.6% unsatisfactory. Conclusion: Although both the techniques could detect malignancy, the oral rub and rinse technique showed better cellular clarity and sample adequacy when compared to conventional exfoliative cytology, which makes it a practical tool in resource-challenged settings. |
| first_indexed | 2024-04-11T10:55:14Z |
| format | Article |
| id | doaj.art-4bcff1a9abfc45e189da83d4761a2228 |
| institution | Directory Open Access Journal |
| issn | 0975-8844 |
| language | English |
| last_indexed | 2024-04-11T10:55:14Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Orofacial Sciences |
| spelling | doaj.art-4bcff1a9abfc45e189da83d4761a22282022-12-22T04:28:48ZengWolters Kluwer Medknow PublicationsJournal of Orofacial Sciences0975-88442022-01-01141626510.4103/jofs.jofs_43_22Effectiveness of a New Technique for Oral Cancer Screening – A Pilot StudyAudrey Madonna D’CruzPushparaja ShettyUrvashi Ashwin ShettyVinayak Kamath BolaVishnudas Dinesh PrabhuIntroduction: Screening programs with the use of specific diagnostic tools in asymptomatic patients are useful in identifying suspicious oral lesions and aid in the early diagnosis of oral cancer. The objective of the present study was to compare the oral rub and rinse technique with the conventional exfoliative cytology in the screening of oral malignant and potentially malignant diseases. Materials and Methods: An oral cancer screening program was conducted in the Dakshina Kannada district of Karnataka, India. The oral rub and rinse technique was performed on patients who had red/white lesions in the oral mucosa followed by the conventional exfoliative cytology. Scalpel biopsy was performed to confirm for presence or absence of malignancy in cases wherever indicated. Descriptive statistics (frequency and percentage) were used in the present study. Results: A total of 848 subjects were screened for oral cancer and precancer. About 112 participants had premalignant/malignant lesions and biopsy was performed on 30 subjects. Of these, 27.7% were Class I smears, 39.3% were Class II smears, 22.3% were Class III smears, 4.5% were Class IV smears, and 6.2% were unsatisfactory using the conventional technique, whereas the oral rub and rinse technique showed 26.8% Class I smears, 42.9% Class II smears, 19.6% Class III smears, 6.2% Class IV smears, 0.9% Class V smears, and 3.6% unsatisfactory. Conclusion: Although both the techniques could detect malignancy, the oral rub and rinse technique showed better cellular clarity and sample adequacy when compared to conventional exfoliative cytology, which makes it a practical tool in resource-challenged settings.http://www.jofs.in/article.asp?issn=0975-8844;year=2022;volume=14;issue=1;spage=62;epage=65;aulast=D’Cruzcytologyearly diagnosismouth neoplasmoral cancer screening |
| spellingShingle | Audrey Madonna D’Cruz Pushparaja Shetty Urvashi Ashwin Shetty Vinayak Kamath Bola Vishnudas Dinesh Prabhu Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study Journal of Orofacial Sciences cytology early diagnosis mouth neoplasm oral cancer screening |
| title | Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study |
| title_full | Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study |
| title_fullStr | Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study |
| title_full_unstemmed | Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study |
| title_short | Effectiveness of a New Technique for Oral Cancer Screening – A Pilot Study |
| title_sort | effectiveness of a new technique for oral cancer screening a pilot study |
| topic | cytology early diagnosis mouth neoplasm oral cancer screening |
| url | http://www.jofs.in/article.asp?issn=0975-8844;year=2022;volume=14;issue=1;spage=62;epage=65;aulast=D’Cruz |
| work_keys_str_mv | AT audreymadonnadcruz effectivenessofanewtechniquefororalcancerscreeningapilotstudy AT pushparajashetty effectivenessofanewtechniquefororalcancerscreeningapilotstudy AT urvashiashwinshetty effectivenessofanewtechniquefororalcancerscreeningapilotstudy AT vinayakkamathbola effectivenessofanewtechniquefororalcancerscreeningapilotstudy AT vishnudasdineshprabhu effectivenessofanewtechniquefororalcancerscreeningapilotstudy |