Induction of Reactive Bone Stromal Fibroblasts in 3D Models of Prostate Cancer Bone Metastases

A dynamic interplay between prostate cancer (PCa) cells and reactive bone stroma modulates the growth of metastases within the bone microenvironment. Of the stromal cells, metastasis-associated fibroblasts (MAFs) are known to contribute but are the least studied cell type in PCa tumour progression....

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Bibliographic Details
Main Authors: Louisa C. E. Windus, Nicholas Matigian, Vicky M. Avery
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/6/861