Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions

Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions

Abstract Background Neovascular age-related macular degeneration (nAMD) is a major cause of blindness in the elderly. The disease is due to the growth of abnormal blood vessels into the macula, leading to the loss of central vision. Intravitreal injection of vascular endothelial growth factor (VEGF)...

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Bibliographic Details
Main Authors: Wen Deng, Caijiao Yi, Wei Pan, Jian Liu, Jinyan Qi, Juan Chen, Zengchao Zhou, Yiqin Duan, Xiangyan Ning, Jun Li, Changhua Ye, Zhongping Chen, Heping Xu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Immunity & Ageing
Subjects:
Macular fibrosis
Vascular cell adhesion molecule 1
Macrophage
Inflammation
Aqueous humour
Online Access:https://doi.org/10.1186/s12979-023-00389-x

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