Effective Activation by Kynurenic Acid and Its Aminoalkylated Derivatives on M-Type K<sup>+</sup> Current

Effective Activation by Kynurenic Acid and Its Aminoalkylated Derivatives on M-Type K<sup>+</sup> Current

Kynurenic acid (KYNA, 4-oxoquinoline-2-carboxylic acid), an intermediate of the tryptophan metabolism, has been recognized to exert different neuroactive actions; however, the need of how it or its aminoalkylated amide derivative <i>N</i>-(2-(dimethylamino)ethyl)-3-(morpholinomethyl)-4-o...

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Bibliographic Details
Main Authors: Yi-Ching Lo, Chih-Lung Lin, Wei-Yu Fang, Bálint Lőrinczi, István Szatmári, Wan-Hsuan Chang, Ferenc Fülöp, Sheng-Nan Wu
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
kynurenic acid
kynurenic acid derivative
M-type K<sup>+</sup> current
action potential
pituitary cell
hippocampal neuron
Online Access:https://www.mdpi.com/1422-0067/22/3/1300

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https://www.mdpi.com/1422-0067/22/3/1300

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