Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion

Early ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are pote...

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Bibliographic Details
Main Authors: Shail Thanki, Karl A. Kasischke, Maxim Mokin
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Stroke: Vascular and Interventional Neurology
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.121.000197
Description
Summary:Early ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are potentially reversible if successful endovascular reperfusion is performed in a timely manner. This has led to the concept of “ghost infarct core” which is the mismatch in the infarct core as seen on follow‐up imaging. We present a case which potentially supports the concept of “ghost infarct core” evaluated not only by computed tomography perfusion but also non‐contrast computed tomography in a patient with large vessel occlusion following successful thrombectomy.
ISSN:2694-5746