Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
Early ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are pote...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Wiley
2022-07-01
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Series: | Stroke: Vascular and Interventional Neurology |
Online Access: | https://www.ahajournals.org/doi/10.1161/SVIN.121.000197 |
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author | Shail Thanki Karl A. Kasischke Maxim Mokin |
author_facet | Shail Thanki Karl A. Kasischke Maxim Mokin |
author_sort | Shail Thanki |
collection | DOAJ |
description | Early ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are potentially reversible if successful endovascular reperfusion is performed in a timely manner. This has led to the concept of “ghost infarct core” which is the mismatch in the infarct core as seen on follow‐up imaging. We present a case which potentially supports the concept of “ghost infarct core” evaluated not only by computed tomography perfusion but also non‐contrast computed tomography in a patient with large vessel occlusion following successful thrombectomy. |
first_indexed | 2024-03-08T17:54:09Z |
format | Article |
id | doaj.art-4bd59d93330d490a8cb060dac10cbea3 |
institution | Directory Open Access Journal |
issn | 2694-5746 |
language | English |
last_indexed | 2024-03-08T17:54:09Z |
publishDate | 2022-07-01 |
publisher | Wiley |
record_format | Article |
series | Stroke: Vascular and Interventional Neurology |
spelling | doaj.art-4bd59d93330d490a8cb060dac10cbea32024-01-02T05:43:44ZengWileyStroke: Vascular and Interventional Neurology2694-57462022-07-012410.1161/SVIN.121.000197Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular ReperfusionShail Thanki0Karl A. Kasischke1Maxim Mokin2Department of Neurosurgery and Brain Repair University of South Florida Tampa FLDepartment of Neurology University of South Florida Tampa FLDepartment of Neurosurgery and Brain Repair University of South Florida Tampa FLEarly ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are potentially reversible if successful endovascular reperfusion is performed in a timely manner. This has led to the concept of “ghost infarct core” which is the mismatch in the infarct core as seen on follow‐up imaging. We present a case which potentially supports the concept of “ghost infarct core” evaluated not only by computed tomography perfusion but also non‐contrast computed tomography in a patient with large vessel occlusion following successful thrombectomy.https://www.ahajournals.org/doi/10.1161/SVIN.121.000197 |
spellingShingle | Shail Thanki Karl A. Kasischke Maxim Mokin Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion Stroke: Vascular and Interventional Neurology |
title | Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion |
title_full | Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion |
title_fullStr | Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion |
title_full_unstemmed | Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion |
title_short | Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion |
title_sort | apparent reversal of early ischemic changes on non contrast computed tomography following successful endovascular reperfusion |
url | https://www.ahajournals.org/doi/10.1161/SVIN.121.000197 |
work_keys_str_mv | AT shailthanki apparentreversalofearlyischemicchangesonnoncontrastcomputedtomographyfollowingsuccessfulendovascularreperfusion AT karlakasischke apparentreversalofearlyischemicchangesonnoncontrastcomputedtomographyfollowingsuccessfulendovascularreperfusion AT maximmokin apparentreversalofearlyischemicchangesonnoncontrastcomputedtomographyfollowingsuccessfulendovascularreperfusion |