Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion

Early ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are pote...

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Main Authors: Shail Thanki, Karl A. Kasischke, Maxim Mokin
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Stroke: Vascular and Interventional Neurology
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.121.000197
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author Shail Thanki
Karl A. Kasischke
Maxim Mokin
author_facet Shail Thanki
Karl A. Kasischke
Maxim Mokin
author_sort Shail Thanki
collection DOAJ
description Early ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are potentially reversible if successful endovascular reperfusion is performed in a timely manner. This has led to the concept of “ghost infarct core” which is the mismatch in the infarct core as seen on follow‐up imaging. We present a case which potentially supports the concept of “ghost infarct core” evaluated not only by computed tomography perfusion but also non‐contrast computed tomography in a patient with large vessel occlusion following successful thrombectomy.
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spelling doaj.art-4bd59d93330d490a8cb060dac10cbea32024-01-02T05:43:44ZengWileyStroke: Vascular and Interventional Neurology2694-57462022-07-012410.1161/SVIN.121.000197Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular ReperfusionShail Thanki0Karl A. Kasischke1Maxim Mokin2Department of Neurosurgery and Brain Repair University of South Florida Tampa FLDepartment of Neurology University of South Florida Tampa FLDepartment of Neurosurgery and Brain Repair University of South Florida Tampa FLEarly ischemic changes seen on non‐contrast computed tomography secondary to cerebral edema is believed to indicate irreversible cellular injury. Computed tomography perfusion may overpredict the infarct core in patients with large vessel occlusion presenting in acute phase as these changes are potentially reversible if successful endovascular reperfusion is performed in a timely manner. This has led to the concept of “ghost infarct core” which is the mismatch in the infarct core as seen on follow‐up imaging. We present a case which potentially supports the concept of “ghost infarct core” evaluated not only by computed tomography perfusion but also non‐contrast computed tomography in a patient with large vessel occlusion following successful thrombectomy.https://www.ahajournals.org/doi/10.1161/SVIN.121.000197
spellingShingle Shail Thanki
Karl A. Kasischke
Maxim Mokin
Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
Stroke: Vascular and Interventional Neurology
title Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
title_full Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
title_fullStr Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
title_full_unstemmed Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
title_short Apparent Reversal of Early Ischemic Changes on Non‐Contrast Computed Tomography Following Successful Endovascular Reperfusion
title_sort apparent reversal of early ischemic changes on non contrast computed tomography following successful endovascular reperfusion
url https://www.ahajournals.org/doi/10.1161/SVIN.121.000197
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AT karlakasischke apparentreversalofearlyischemicchangesonnoncontrastcomputedtomographyfollowingsuccessfulendovascularreperfusion
AT maximmokin apparentreversalofearlyischemicchangesonnoncontrastcomputedtomographyfollowingsuccessfulendovascularreperfusion