Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer
Abstract Members of the human epidermal growth factor receptor (HER) family play a significant role in bladder cancer progression and may underlie the development of chemotherapy resistance. Dacomitinib is an irreversible tyrosine kinase inhibitor with structural specificity for the catalytic domain...
Główni autorzy: | Petros D. Grivas, Kathleen C. Day, Andreas Karatsinides, Alyssa Paul, Nazia Shakir, Iya Owainati, Monica Liebert, Lakshmi P. Kunju, Dafydd Thomas, Maha Hussain, Mark L. Day |
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Format: | Artykuł |
Język: | English |
Wydane: |
BMC
2013-10-01
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Seria: | Molecular Medicine |
Hasła przedmiotowe: | |
Dostęp online: | https://doi.org/10.2119/molmed.2013.00108 |
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