Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer

Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer

Abstract Members of the human epidermal growth factor receptor (HER) family play a significant role in bladder cancer progression and may underlie the development of chemotherapy resistance. Dacomitinib is an irreversible tyrosine kinase inhibitor with structural specificity for the catalytic domain...

Bibliografiset tiedot
Päätekijät:	Petros D. Grivas, Kathleen C. Day, Andreas Karatsinides, Alyssa Paul, Nazia Shakir, Iya Owainati, Monica Liebert, Lakshmi P. Kunju, Dafydd Thomas, Maha Hussain, Mark L. Day
Aineistotyyppi:	Artikkeli
Kieli:	English
Julkaistu:	BMC 2013-10-01
Sarja:	Molecular Medicine
Aiheet:	Dacomitinib Bladder Cancer Xenografts Non-obese Diabetic/severe Combined Immunodeficiency (NOD/SCID) Epidermal Growth Factor Receptor (EGFR) Lapatinib
Linkit:	https://doi.org/10.2119/molmed.2013.00108

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