Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer

Abstract Members of the human epidermal growth factor receptor (HER) family play a significant role in bladder cancer progression and may underlie the development of chemotherapy resistance. Dacomitinib is an irreversible tyrosine kinase inhibitor with structural specificity for the catalytic domain...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Petros D. Grivas, Kathleen C. Day, Andreas Karatsinides, Alyssa Paul, Nazia Shakir, Iya Owainati, Monica Liebert, Lakshmi P. Kunju, Dafydd Thomas, Maha Hussain, Mark L. Day
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: BMC 2013-10-01
Sraith:Molecular Medicine
Ábhair:
Rochtain ar líne:https://doi.org/10.2119/molmed.2013.00108