Down-Regulation of C1GALT1 Enhances the Progression of Cholangiocarcinoma through Activation of AKT/ERK Signaling Pathways

Down-Regulation of C1GALT1 Enhances the Progression of Cholangiocarcinoma through Activation of AKT/ERK Signaling Pathways

Alteration of mucin-type O-glycosylation is implicated in tumor progression and metastasis of cholangiocarcinoma (CCA). Core 1 β1-3 Galactosyltransferase (C1GALT1) is a primary enzyme that regulates the elongation of core 1-derived mucin-type O-glycans. Dysregulation of C1GALT1 has been documented i...

Full description

Bibliographic Details
Main Authors: Juthamas Khiaowichit, Chutima Talabnin, Chavaboon Dechsukhum, Atit Silsirivanit, Krajang Talabnin
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Life
Subjects:
cholangiocarcinoma
core 1 β1-3 galactosyltransferase 1 (C1GALT1)
cancer aggressiveness
Online Access:https://www.mdpi.com/2075-1729/12/2/174

Similar Items

Similar Items