Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats
In this study, the effects of bovine corpus vitreum on wound healing were examined macroscopically and histopathologically. The study was carried out on 28 adult rats (Rattus norvegicus) weighing 150-300 g. Using general anesthesia, two separate wound excisions of 1 cm in diameter were formed in the...
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| Format: | Article |
| Language: | English |
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Kafkas University, Faculty of Veterinary Medicine
2017-10-01
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| Series: | Kafkas Universitesi Veteriner Fakültesi Dergisi |
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| Online Access: | https://vetdergikafkas.org/pdf.php?id=2208 |
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| author | Celal Şahin ERMUTLU Engin KILIÇ Özgür AKSOY Sadık YAYLA Vedat BARAN Serpil DAĞ Muzaffer Başak ULKAY Uğur AYDIN Berjan DEMİRTAŞ |
| author_facet | Celal Şahin ERMUTLU Engin KILIÇ Özgür AKSOY Sadık YAYLA Vedat BARAN Serpil DAĞ Muzaffer Başak ULKAY Uğur AYDIN Berjan DEMİRTAŞ |
| author_sort | Celal Şahin ERMUTLU |
| collection | DOAJ |
| description | In this study, the effects of bovine corpus vitreum on wound healing were examined macroscopically and histopathologically. The study was carried
out on 28 adult rats (Rattus norvegicus) weighing 150-300 g. Using general anesthesia, two separate wound excisions of 1 cm in diameter were formed
in the right and left back halves of all rats. In the control group, the wound care was performed only by dripping serum over the wound daily. In the
study group, the corpus vitreum obtained from newly cut healthy cows in the slaughterhouse was applied to the wound surface. All injuries were
photographed using digital camera on days 1, 3, 5, 7, 9, 11, 13 and 15 and wound surface areas were compared. At the end of the first and second
weeks, tissue samples taken from wound beds were examined histopathologically and the results were evaluated statistically. According to the
wound surface area measurements and histopathologic results, corpus vitreum was found to have a positive effect on wound healing and a faster
and more regular healing was achieved in the wounds compared to the control group. |
| first_indexed | 2024-03-13T04:37:13Z |
| format | Article |
| id | doaj.art-4bdadea39fd643ecbc5ff4b044c86b98 |
| institution | Directory Open Access Journal |
| issn | 1309-2251 |
| language | English |
| last_indexed | 2024-03-13T04:37:13Z |
| publishDate | 2017-10-01 |
| publisher | Kafkas University, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| spelling | doaj.art-4bdadea39fd643ecbc5ff4b044c86b982023-06-19T06:44:24ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512017-10-01241333810.9775/kvfd.2017.181892208Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in ratsCelal Şahin ERMUTLU0Engin KILIÇ1Özgür AKSOY2Sadık YAYLA3Vedat BARAN4Serpil DAĞ5Muzaffer Başak ULKAY6Uğur AYDIN7Berjan DEMİRTAŞ8Kafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Pathology, TR-36100 Kars - TURKEYİstanbul University, Faculty of Veterinary Medicine, Department of Histology and Embryology, TR-34320 İstanbul - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYİstanbul University, Vocational School of Veterinary Medicine, TR-34320 İstanbul - TURKEYIn this study, the effects of bovine corpus vitreum on wound healing were examined macroscopically and histopathologically. The study was carried out on 28 adult rats (Rattus norvegicus) weighing 150-300 g. Using general anesthesia, two separate wound excisions of 1 cm in diameter were formed in the right and left back halves of all rats. In the control group, the wound care was performed only by dripping serum over the wound daily. In the study group, the corpus vitreum obtained from newly cut healthy cows in the slaughterhouse was applied to the wound surface. All injuries were photographed using digital camera on days 1, 3, 5, 7, 9, 11, 13 and 15 and wound surface areas were compared. At the end of the first and second weeks, tissue samples taken from wound beds were examined histopathologically and the results were evaluated statistically. According to the wound surface area measurements and histopathologic results, corpus vitreum was found to have a positive effect on wound healing and a faster and more regular healing was achieved in the wounds compared to the control group.https://vetdergikafkas.org/pdf.php?id=2208bovine corpus vitreumwound healingrat |
| spellingShingle | Celal Şahin ERMUTLU Engin KILIÇ Özgür AKSOY Sadık YAYLA Vedat BARAN Serpil DAĞ Muzaffer Başak ULKAY Uğur AYDIN Berjan DEMİRTAŞ Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats Kafkas Universitesi Veteriner Fakültesi Dergisi bovine corpus vitreum wound healing rat |
| title | Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats |
| title_full | Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats |
| title_fullStr | Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats |
| title_full_unstemmed | Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats |
| title_short | Effect of bovine corpus vitreum on full-thickness dermal wound healing: an experimental study in rats |
| title_sort | effect of bovine corpus vitreum on full thickness dermal wound healing an experimental study in rats |
| topic | bovine corpus vitreum wound healing rat |
| url | https://vetdergikafkas.org/pdf.php?id=2208 |
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