Pulmonary biology of anti-interleukin 5 antibodies

Pulmonary biology of anti-interleukin 5 antibodies

Interleukin 5 (IL-5) is a critical cytokine for the maturation of eosinophil precursors to eosinophils in the bone marrow and those eosinophils then accumulate in the lungs during asthma. We have studied anti IL-5 antibodies on allergic responses in mice, guinea pigs and monkeys and are extending th...

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Bibliographic Details
Main Authors:	RW Egan, D Athwahl, C-C Chou, RW Chapman, S Emtage, C-H Jenh, TT Kung, PJ Mauser, NJ Murgolo, MW Bodmer
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 1997-12-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	eosinophils interleukin-5 pulmonary inflammation antibodies airway hyperresponsiveness
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761997000800011

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