The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

<p>Abstract</p> <p>Background</p> <p>Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested explanations focus on variat...

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Bibliographic Details
Main Author: Stoletzki Nina
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Evolutionary Biology
Subjects:
GC-biased gene conversion
optimal codon use
cause of correlation
Online Access:http://www.biomedcentral.com/1471-2148/11/93

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