Theory Designed Strategies to Support Implementation of Genomics in Nephrology
(1) Background: Genomic testing is increasingly utilized as a clinical tool; however, its integration into nephrology remains limited. The purpose of this study was to identify barriers and prioritize interventions for the widespread implementation of genomics in nephrology. (2) Methods: Qualitative...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Genes |
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| Online Access: | https://www.mdpi.com/2073-4425/13/10/1919 |
| _version_ | 1797473125640699904 |
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| author | Arushi Kansal Catherine Quinlan Zornitza Stark Peter G. Kerr Andrew J. Mallett Chandni Lakshmanan Stephanie Best Kushani Jayasinghe |
| author_facet | Arushi Kansal Catherine Quinlan Zornitza Stark Peter G. Kerr Andrew J. Mallett Chandni Lakshmanan Stephanie Best Kushani Jayasinghe |
| author_sort | Arushi Kansal |
| collection | DOAJ |
| description | (1) Background: Genomic testing is increasingly utilized as a clinical tool; however, its integration into nephrology remains limited. The purpose of this study was to identify barriers and prioritize interventions for the widespread implementation of genomics in nephrology. (2) Methods: Qualitative, semi-structured interviews were conducted with 25 Australian adult nephrologists to determine their perspectives on interventions and models of care to support implementation of genomics in nephrology. Interviews were guided by a validated theoretical framework for the implementation of genomic medicine—the Consolidated Framework of Implementation Research (CFIR). (3) Results: Nephrologists were from 18 hospitals, with 7 having a dedicated multidisciplinary kidney genetics service. Most practiced in the public healthcare system (n = 24), a large number were early-career (n = 13), and few had genomics experience (n = 4). The top three preferred interventions were increased funding, access to genomics champions, and education and training. Where interventions to barriers were not reported, we used the CFIR/Expert Recommendations for Implementing Change matching tool to generate theory-informed approaches. The preferred model of service delivery was a multidisciplinary kidney genetics clinic. (4) Conclusions: This study identified surmountable barriers and practical interventions for the implementation of genomics in nephrology, with multidisciplinary kidney genetics clinics identified as the preferred model of care. The integration of genomics education into nephrology training, secure funding for testing, and counselling along with the identification of genomics champions should be pursued by health services more broadly. |
| first_indexed | 2024-03-09T20:10:31Z |
| format | Article |
| id | doaj.art-4be3962f2a8243df9b54d1e64c929abe |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-09T20:10:31Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-4be3962f2a8243df9b54d1e64c929abe2023-11-24T00:17:21ZengMDPI AGGenes2073-44252022-10-011310191910.3390/genes13101919Theory Designed Strategies to Support Implementation of Genomics in NephrologyArushi Kansal0Catherine Quinlan1Zornitza Stark2Peter G. Kerr3Andrew J. Mallett4Chandni Lakshmanan5Stephanie Best6Kushani Jayasinghe7Department of Nephrology, Monash Health, Melbourne 3168, AustraliaKidney Regeneration, Murdoch Children’s Research Institute, Melbourne 3052, AustraliaThe KidGen Collaborative, Australian Genomics Health Alliance, Melbourne 3052, AustraliaDepartment of Nephrology, Monash Health, Melbourne 3168, AustraliaThe KidGen Collaborative, Australian Genomics Health Alliance, Melbourne 3052, AustraliaNorthern Health, Melbourne 3076, AustraliaAustralian Genomics Health Alliance, Melbourne 3052, AustraliaDepartment of Nephrology, Monash Health, Melbourne 3168, Australia(1) Background: Genomic testing is increasingly utilized as a clinical tool; however, its integration into nephrology remains limited. The purpose of this study was to identify barriers and prioritize interventions for the widespread implementation of genomics in nephrology. (2) Methods: Qualitative, semi-structured interviews were conducted with 25 Australian adult nephrologists to determine their perspectives on interventions and models of care to support implementation of genomics in nephrology. Interviews were guided by a validated theoretical framework for the implementation of genomic medicine—the Consolidated Framework of Implementation Research (CFIR). (3) Results: Nephrologists were from 18 hospitals, with 7 having a dedicated multidisciplinary kidney genetics service. Most practiced in the public healthcare system (n = 24), a large number were early-career (n = 13), and few had genomics experience (n = 4). The top three preferred interventions were increased funding, access to genomics champions, and education and training. Where interventions to barriers were not reported, we used the CFIR/Expert Recommendations for Implementing Change matching tool to generate theory-informed approaches. The preferred model of service delivery was a multidisciplinary kidney genetics clinic. (4) Conclusions: This study identified surmountable barriers and practical interventions for the implementation of genomics in nephrology, with multidisciplinary kidney genetics clinics identified as the preferred model of care. The integration of genomics education into nephrology training, secure funding for testing, and counselling along with the identification of genomics champions should be pursued by health services more broadly.https://www.mdpi.com/2073-4425/13/10/1919genomicsnephrologytheory designed strategies |
| spellingShingle | Arushi Kansal Catherine Quinlan Zornitza Stark Peter G. Kerr Andrew J. Mallett Chandni Lakshmanan Stephanie Best Kushani Jayasinghe Theory Designed Strategies to Support Implementation of Genomics in Nephrology Genes genomics nephrology theory designed strategies |
| title | Theory Designed Strategies to Support Implementation of Genomics in Nephrology |
| title_full | Theory Designed Strategies to Support Implementation of Genomics in Nephrology |
| title_fullStr | Theory Designed Strategies to Support Implementation of Genomics in Nephrology |
| title_full_unstemmed | Theory Designed Strategies to Support Implementation of Genomics in Nephrology |
| title_short | Theory Designed Strategies to Support Implementation of Genomics in Nephrology |
| title_sort | theory designed strategies to support implementation of genomics in nephrology |
| topic | genomics nephrology theory designed strategies |
| url | https://www.mdpi.com/2073-4425/13/10/1919 |
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