Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice.
Hydrogen sulfide (H(2)S), a novel gaseous messenger, is synthesized endogenously from L-cysteine by two pyridoxal-5'-phosphate-dependent enzymes, cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE). S-propargyl-cysteine (SPRC) is a slow H(2)S releasing drug that provides cysteine, a...
Main Authors: | Jenab N Sidhapuriwala, Akhil Hegde, Abel D Ang, Yi Zhun Zhu, Madhav Bhatia |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3291555?pdf=render |
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