Elevated Exhaustion Levels of NK and CD8+ T Cells as Indicators for Progression and Prognosis of COVID-19 Disease

Elevated Exhaustion Levels of NK and CD8+ T Cells as Indicators for Progression and Prognosis of COVID-19 Disease

BackgroundSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induced Coronavirus Disease 2019 (COVID-19) has posed a global threat to public health. The immune system is crucial in defending and eliminating the virus and infected cells. However, immune dysregulation may result in the rapid...

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Bibliographic Details
Main Authors: Mingyue Li, Weina Guo, Yalan Dong, Xiaobei Wang, Die Dai, Xingxing Liu, Yiquan Wu, Mengmeng Li, Wenjing Zhang, Haifeng Zhou, Zili Zhang, Lan Lin, Zhenyu Kang, Ting Yu, Chunxia Tian, Renjie Qin, Yang Gui, Feng Jiang, Heng Fan, Vigo Heissmeyer, Alexey Sarapultsev, Lin Wang, Shanshan Luo, Desheng Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
COVID-19
natural killer (NK) cells
T cells
exhaustion
prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.580237/full

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