Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images

Recent advances in deep learning, coupled with the onslaught of unlabelled medical data have drawn ever-increasing research interests by discovering multiple levels of distributed representations and solving complex medical related problems. Malaria disease detection in early stage requires an accur...

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Main Authors: Priyadarshini Adyasha Pattanaik, Mohit Mittal, Mohammad Zubair Khan
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9097238/
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author Priyadarshini Adyasha Pattanaik
Mohit Mittal
Mohammad Zubair Khan
author_facet Priyadarshini Adyasha Pattanaik
Mohit Mittal
Mohammad Zubair Khan
author_sort Priyadarshini Adyasha Pattanaik
collection DOAJ
description Recent advances in deep learning, coupled with the onslaught of unlabelled medical data have drawn ever-increasing research interests by discovering multiple levels of distributed representations and solving complex medical related problems. Malaria disease detection in early stage requires an accurate and precise diagnosis in order to achieve successful patient remission. This paper proposes a comprehensive computer-aided diagnosis (CAD) scheme for identifying the presence of malaria parasites in thick blood smear images. The parameters of the scheme are pre-trained by functional link artificial neural network followed by sparse stacked autoencoder. The optimum size of the CAD scheme used in this research is 12500-2500-100-50-2, where the input layer has 12500 nodes and Softmax classifier output layer has 2 nodes. Moreover, the 10- fold cross validation reflects that the classification is reliable and is applicable to new patient blood smear images. The proposed CAD scheme has been evaluated using malaria blood smear image data set, achieving a detection accuracy of 89.10%, a sensitivity of 93.90% and specificity of 83.10%. The extensive comparative experiment suggests that the proposed CAD scheme provides richer effectiveness and efficiency for malaria data set compared to other deep learning techniques for better diagnosis decision and management. This work implements a novel approach to fast processing and will be a beneficial tool in disease identification.
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spelling doaj.art-4bec5b8b65214457bf50567e9183252e2022-12-21T18:20:06ZengIEEEIEEE Access2169-35362020-01-018949369494610.1109/ACCESS.2020.29960229097238Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic ImagesPriyadarshini Adyasha Pattanaik0Mohit Mittal1https://orcid.org/0000-0003-0878-4615Mohammad Zubair Khan2https://orcid.org/0000-0002-2409-7172Telecom SudParis, Évry, FranceDepartment of Information Science and Engineering, Kyoto Sangyo University, Kyoto, JapanDepartment of Computer Science, College of Computer Science and Engineering, Taibah University, Madinah, Saudi ArabiaRecent advances in deep learning, coupled with the onslaught of unlabelled medical data have drawn ever-increasing research interests by discovering multiple levels of distributed representations and solving complex medical related problems. Malaria disease detection in early stage requires an accurate and precise diagnosis in order to achieve successful patient remission. This paper proposes a comprehensive computer-aided diagnosis (CAD) scheme for identifying the presence of malaria parasites in thick blood smear images. The parameters of the scheme are pre-trained by functional link artificial neural network followed by sparse stacked autoencoder. The optimum size of the CAD scheme used in this research is 12500-2500-100-50-2, where the input layer has 12500 nodes and Softmax classifier output layer has 2 nodes. Moreover, the 10- fold cross validation reflects that the classification is reliable and is applicable to new patient blood smear images. The proposed CAD scheme has been evaluated using malaria blood smear image data set, achieving a detection accuracy of 89.10%, a sensitivity of 93.90% and specificity of 83.10%. The extensive comparative experiment suggests that the proposed CAD scheme provides richer effectiveness and efficiency for malaria data set compared to other deep learning techniques for better diagnosis decision and management. This work implements a novel approach to fast processing and will be a beneficial tool in disease identification.https://ieeexplore.ieee.org/document/9097238/Computer-aided diagnosis (CAD)Deep learningmalaria parasite detectionmicroscopic blood smear imagesdigital pathologyK-fold cross-validation
spellingShingle Priyadarshini Adyasha Pattanaik
Mohit Mittal
Mohammad Zubair Khan
Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images
IEEE Access
Computer-aided diagnosis (CAD)
Deep learning
malaria parasite detection
microscopic blood smear images
digital pathology
K-fold cross-validation
title Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images
title_full Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images
title_fullStr Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images
title_full_unstemmed Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images
title_short Unsupervised Deep Learning CAD Scheme for the Detection of Malaria in Blood Smear Microscopic Images
title_sort unsupervised deep learning cad scheme for the detection of malaria in blood smear microscopic images
topic Computer-aided diagnosis (CAD)
Deep learning
malaria parasite detection
microscopic blood smear images
digital pathology
K-fold cross-validation
url https://ieeexplore.ieee.org/document/9097238/
work_keys_str_mv AT priyadarshiniadyashapattanaik unsuperviseddeeplearningcadschemeforthedetectionofmalariainbloodsmearmicroscopicimages
AT mohitmittal unsuperviseddeeplearningcadschemeforthedetectionofmalariainbloodsmearmicroscopicimages
AT mohammadzubairkhan unsuperviseddeeplearningcadschemeforthedetectionofmalariainbloodsmearmicroscopicimages