Weighted gene co-expression identification of CDKN1A as a hub inflammation gene following cardiopulmonary bypass in children with congenital heart disease

Weighted gene co-expression identification of CDKN1A as a hub inflammation gene following cardiopulmonary bypass in children with congenital heart disease

BackgroundCongenital heart disease (CHD) is the most common type of birth defect. Most patients with CHD require surgery, and cardiopulmonary bypass (CPB) is the most common surgery performed.MethodsThe present study utilized weighted gene co-expression network analysis (WGCNA) to identify key infla...

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Bibliographic Details
Main Authors: Huan Chen, Jinglan Liu, Yuqing Wu, Li Jiang, Mi Tang, Xin Wang, Xiaoling Fang, Xi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Surgery
Subjects:
cardiopulmonary bypass
WGCNA
hub genes
CDKN1A
congenital heart disease
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.963850/full

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