IgG Protease Mac/IdeS Is Not Essential for Phagocyte Resistance or Mouse Virulence of M1T1 Group A <italic toggle="yes">Streptococcus</italic>

IgG Protease Mac/IdeS Is Not Essential for Phagocyte Resistance or Mouse Virulence of M1T1 Group A <italic toggle="yes">Streptococcus</italic>

ABSTRACT The Mac/IdeS protein of group A Streptococcus (GAS) is a secreted cysteine protease with cleavage specificity for IgG and is highly expressed in the GAS serotype M1T1 clone, which is the serotype most frequently isolated from patients with life-threatening invasive infections. While studies...

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Bibliographic Details
Main Authors:	Cheryl Y. M. Okumura, Ericka L. Anderson, Simon Döhrmann, Dan N. Tran, Joshua Olson, Ulrich von Pawel-Rammingen, Victor Nizet
Format:	Article
Language:	English
Published:	American Society for Microbiology 2013-08-01
Series:	mBio
Online Access:	https://journals.asm.org/doi/10.1128/mBio.00499-13

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