Approaches to handling missing or “problematic” pharmacology data: Pharmacokinetics
Abstract Missing or erroneous information is a common problem in the analysis of pharmacokinetic (PK) data. This may present as missing or inaccurate dose level or dose time, drug concentrations below the analytical limit of quantification, missing sample times, or missing or incorrect covariate inf...
Main Authors: | Donald J. Irby, Mustafa E. Ibrahim, Anees M. Dauki, Mohamed A. Badawi, Sílvia M. Illamola, Mingqing Chen, Yuhuan Wang, Xiaoxi Liu, Mitch A. Phelps, Diane R. Mould |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-04-01
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Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12611 |
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