Combined Methylation and Transcriptome Analysis of Liver Injury of Nonalcoholic Fatty Liver Disease Induced by High Alcohol-Producing Klebsiella pneumoniae

Combined Methylation and Transcriptome Analysis of Liver Injury of Nonalcoholic Fatty Liver Disease Induced by High Alcohol-Producing Klebsiella pneumoniae

ABSTRACT It has been known that high alcohol-producing Klebsiella pneumoniae (HiAlc Kpn) is one of causative agents of nonalcoholic fatty liver disease (NAFLD). However, how HiAlc Kpn promotes liver injury remains unclear. Recent findings suggest that DNA methylation might associate with the pathoge...

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Bibliographic Details
Main Authors: Rui Zhang, Ziying Xu, Guanhua Xue, Junxia Feng, Bing Du, Lin Gan, Zheng Fan, Tongtong Fu, Yanling Feng, Hanqing Zhao, Jinghua Cui, Chao Yan, Xiaohu Cui, Ziyan Tian, Jinfeng Chen, Zihui Yu, Jing Yuan
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
HiAlc Kpn
endogenous ethanol
DNA methylation
liver injury
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05323-22

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