An integrative multi-omics network-based approach identifies key regulators for breast cancer

An integrative multi-omics network-based approach identifies key regulators for breast cancer

Although genome-wide association studies (GWASs) have successfully identified thousands of risk variants for human complex diseases, understanding the biological function and molecular mechanisms of the associated SNPs involved in complex diseases is challenging. Here we developed a framework named...

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Bibliographic Details
Main Authors: Yi-Xiao Chen, Hao Chen, Yu Rong, Feng Jiang, Jia-Bin Chen, Yuan-Yuan Duan, Dong-Li Zhu, Tie-Lin Yang, Zhijun Dai, Shan-Shan Dong, Yan Guo
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Regulatory network
Breast cancer
Multi-omics
Integrative network-based approach
GWASs
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020304220

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