Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm

Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm

All animals have body burdens of polychlorinated biphenyls (PCBs) despite their ban decades ago. These and modern endocrine-disrupting chemicals (EDCs) such as the fungicide vinclozolin (VIN) perturb hormone signaling and lead to dysfunctions following prenatal exposures. Beyond direct exposures, tr...

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Bibliographic Details
Main Authors: Ross Gillette, Min Ji Son, Lexi Ton, Andrea C. Gore, David Crews
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Epigenetics
Subjects:
endocrine disrupting chemicals
vinclozolin
polychlorinated biphenyls
aroclor
dna methylation
rrbs
transgenerational
inheritance
sperm
brain
Online Access:http://dx.doi.org/10.1080/15592294.2018.1543506

Internet

http://dx.doi.org/10.1080/15592294.2018.1543506

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