Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract
The synthesis of metal oxide nanocomposite by using the green method has gotten special consideration due to a cheaper and eco-friendly approach. Decreasing antibiotic effectiveness calls for the fast advancement of other alternative antimicrobials. CuO, ZnO, and CuO/ZnO nanocomposites were successf...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2023/3481389 |
| _version_ | 1797741053557604352 |
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| author | Elias Takele Raji Feyisa Bogale Gemechu Shumi Girmaye Kenasa |
| author_facet | Elias Takele Raji Feyisa Bogale Gemechu Shumi Girmaye Kenasa |
| author_sort | Elias Takele |
| collection | DOAJ |
| description | The synthesis of metal oxide nanocomposite by using the green method has gotten special consideration due to a cheaper and eco-friendly approach. Decreasing antibiotic effectiveness calls for the fast advancement of other alternative antimicrobials. CuO, ZnO, and CuO/ZnO nanocomposites were successfully synthesized using Zingiber officinale rhizome extract as a mild, renewable, and nontoxic reducing agent and proficient stabilizer with the nonappearance of hazardous and toxic chemicals. UV-Vis spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, and X-ray diffraction (XRD) were used to characterize CuO, ZnO, and CuO/ZnO nanocomposites. The UV-Visible result showed the absorbance peak at 270 nm, 355 nm, 365 nm, and 370 nm corresponding to the characteristic band of CuO NPs, ZnO NPs, 10% CuO/ZnO, and 20% CuO/ZnO nanocomposites, respectively. FT-IR confirmed the nature of bonds and the presence of different functional groups in the Zingiber officinale rhizome extract, CuO, ZnO, and CuO/ZnO nanocomposites. The XRD analysis revealed that all the synthesized particles have a crystalline nature with a particle size of 4.35 nm, 14.54 nm, 18.41 nm, and 20.50 nm of CuO NPs, ZnO NPs, 10% CuO/ZnO, and 20% CuO/ZnO NCs, respectively. The synthesized nanoparticles and nanocomposites showed inhibition against Gram-positive and Gram-negative bacteria up to a concentration of 12.5 mg/mL. The highest inhibition against Staphylococcus aureus ATCC 25926 and Escherichia coli ATCC was 20 ± 0.7 mm and 16 ± 0.5 mm in diameter, respectively, by 50 mg/mL of 20% CuO/ZnO NCs. In general, the biosynthesized nanoparticles and nanocomposites showed effective antibacterial activity. |
| first_indexed | 2024-03-12T14:21:20Z |
| format | Article |
| id | doaj.art-4c0608dd2a36438bba33afeebfe1b923 |
| institution | Directory Open Access Journal |
| issn | 2090-9071 |
| language | English |
| last_indexed | 2024-03-12T14:21:20Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj.art-4c0608dd2a36438bba33afeebfe1b9232023-08-19T00:00:03ZengHindawi LimitedJournal of Chemistry2090-90712023-01-01202310.1155/2023/3481389Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome ExtractElias Takele0Raji Feyisa Bogale1Gemechu Shumi2Girmaye Kenasa3Department of ChemistryDepartment of ChemistryDepartment of ChemistryDepartment of BiologyThe synthesis of metal oxide nanocomposite by using the green method has gotten special consideration due to a cheaper and eco-friendly approach. Decreasing antibiotic effectiveness calls for the fast advancement of other alternative antimicrobials. CuO, ZnO, and CuO/ZnO nanocomposites were successfully synthesized using Zingiber officinale rhizome extract as a mild, renewable, and nontoxic reducing agent and proficient stabilizer with the nonappearance of hazardous and toxic chemicals. UV-Vis spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, and X-ray diffraction (XRD) were used to characterize CuO, ZnO, and CuO/ZnO nanocomposites. The UV-Visible result showed the absorbance peak at 270 nm, 355 nm, 365 nm, and 370 nm corresponding to the characteristic band of CuO NPs, ZnO NPs, 10% CuO/ZnO, and 20% CuO/ZnO nanocomposites, respectively. FT-IR confirmed the nature of bonds and the presence of different functional groups in the Zingiber officinale rhizome extract, CuO, ZnO, and CuO/ZnO nanocomposites. The XRD analysis revealed that all the synthesized particles have a crystalline nature with a particle size of 4.35 nm, 14.54 nm, 18.41 nm, and 20.50 nm of CuO NPs, ZnO NPs, 10% CuO/ZnO, and 20% CuO/ZnO NCs, respectively. The synthesized nanoparticles and nanocomposites showed inhibition against Gram-positive and Gram-negative bacteria up to a concentration of 12.5 mg/mL. The highest inhibition against Staphylococcus aureus ATCC 25926 and Escherichia coli ATCC was 20 ± 0.7 mm and 16 ± 0.5 mm in diameter, respectively, by 50 mg/mL of 20% CuO/ZnO NCs. In general, the biosynthesized nanoparticles and nanocomposites showed effective antibacterial activity.http://dx.doi.org/10.1155/2023/3481389 |
| spellingShingle | Elias Takele Raji Feyisa Bogale Gemechu Shumi Girmaye Kenasa Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract Journal of Chemistry |
| title | Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract |
| title_full | Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract |
| title_fullStr | Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract |
| title_full_unstemmed | Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract |
| title_short | Green Synthesis, Characterization, and Antibacterial Activity of CuO/ZnO Nanocomposite Using Zingiber officinale Rhizome Extract |
| title_sort | green synthesis characterization and antibacterial activity of cuo zno nanocomposite using zingiber officinale rhizome extract |
| url | http://dx.doi.org/10.1155/2023/3481389 |
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