Granular Cell Tumor on Perianal Region: A Case Report
Granular cell tumor (GCT) was first described by Abrikossoff in 1926. GCT is a rarely seen soft tissue tumor and is generally benign. While the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. GCT is rarely seen in the anal...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2013-07-01
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| Series: | Acta Medica Iranica |
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| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/4402 |
| _version_ | 1818237541514477568 |
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| author | Kesici Ugur Mataraci Emine Kesici Sevgi Zeren Sezgin |
| author_facet | Kesici Ugur Mataraci Emine Kesici Sevgi Zeren Sezgin |
| author_sort | Kesici Ugur |
| collection | DOAJ |
| description | Granular cell tumor (GCT) was first described by Abrikossoff in 1926. GCT is a rarely seen soft tissue tumor and is generally benign. While the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. GCT is rarely seen in the anal-perianal region. In accordance with literature this case was reported because it was thought to be the 27th anal-perianal located GCT case. In this case report, approximately 0,5-1 cm pedunculated polypoid lesion was determined in the perianal region during the physical examination of a 23 year old female patient who applied with palpable mass complaint in the perianal region. Lesion in the patient was totally excited with healthy skin-subcutaneous tissue under local anesthesia. A benign granular cell tumor was detected in the histopathological examination. Positive staining was monitored immunohistochemically with S-100 and neuron specific enolase (NSE). GCT is a rarely seen tumor in the anal-perianal region and its malign transformation rate is very low. Even lesions seen in the perianal region have clinically a benign appearance, a histopathological examination should be conducted and also GCT should be kept in mind during diagnosis. Malign-benign separation of these lesions is difficult so histopathological examination should be conducted with great care. Large local excision in the treatment provides curative treatment. But for those presenting malign transformation further examination must be performed for metastasis. After the treatment local recurrence and metastasis should be considered carefully. Prognosis of metastatic disease is very bad. |
| first_indexed | 2024-12-12T12:27:24Z |
| format | Article |
| id | doaj.art-4c06c12bcbc9413996c69838a83f10ca |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-12T12:27:24Z |
| publishDate | 2013-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-4c06c12bcbc9413996c69838a83f10ca2022-12-22T00:24:30ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942013-07-015174355Granular Cell Tumor on Perianal Region: A Case ReportKesici Ugur0Mataraci Emine1Kesici Sevgi2Zeren Sezgin3Department of General Surgery, Ministry of Health, Akcaabat Hackali Baba State Hospital, Trabzon, Turkey.Department of Pathology, Ministry of Health, Akcaabat Hackali Baba State Hospital, Trabzon, Turkey.Department of Anaesthesiology and Reanimation, Ministry of Health, Kanuni Training and Research Hospital, Trabzon, Turkey.Department of General Surgery,Ministry of Health, Numune Hospital, Sivas, Turkey.Granular cell tumor (GCT) was first described by Abrikossoff in 1926. GCT is a rarely seen soft tissue tumor and is generally benign. While the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. GCT is rarely seen in the anal-perianal region. In accordance with literature this case was reported because it was thought to be the 27th anal-perianal located GCT case. In this case report, approximately 0,5-1 cm pedunculated polypoid lesion was determined in the perianal region during the physical examination of a 23 year old female patient who applied with palpable mass complaint in the perianal region. Lesion in the patient was totally excited with healthy skin-subcutaneous tissue under local anesthesia. A benign granular cell tumor was detected in the histopathological examination. Positive staining was monitored immunohistochemically with S-100 and neuron specific enolase (NSE). GCT is a rarely seen tumor in the anal-perianal region and its malign transformation rate is very low. Even lesions seen in the perianal region have clinically a benign appearance, a histopathological examination should be conducted and also GCT should be kept in mind during diagnosis. Malign-benign separation of these lesions is difficult so histopathological examination should be conducted with great care. Large local excision in the treatment provides curative treatment. But for those presenting malign transformation further examination must be performed for metastasis. After the treatment local recurrence and metastasis should be considered carefully. Prognosis of metastatic disease is very bad.https://acta.tums.ac.ir/index.php/acta/article/view/4402Granullar cell tumorSoft tissue neoplasmsPerianal region |
| spellingShingle | Kesici Ugur Mataraci Emine Kesici Sevgi Zeren Sezgin Granular Cell Tumor on Perianal Region: A Case Report Acta Medica Iranica Granullar cell tumor Soft tissue neoplasms Perianal region |
| title | Granular Cell Tumor on Perianal Region: A Case Report |
| title_full | Granular Cell Tumor on Perianal Region: A Case Report |
| title_fullStr | Granular Cell Tumor on Perianal Region: A Case Report |
| title_full_unstemmed | Granular Cell Tumor on Perianal Region: A Case Report |
| title_short | Granular Cell Tumor on Perianal Region: A Case Report |
| title_sort | granular cell tumor on perianal region a case report |
| topic | Granullar cell tumor Soft tissue neoplasms Perianal region |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/4402 |
| work_keys_str_mv | AT kesiciugur granularcelltumoronperianalregionacasereport AT mataraciemine granularcelltumoronperianalregionacasereport AT kesicisevgi granularcelltumoronperianalregionacasereport AT zerensezgin granularcelltumoronperianalregionacasereport |