The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit
Background: In general clinical practice, neonatal seizures are identified visually by direct clinical observation. The study aimed to examine the frequency of clinical seizures in paroxysmal events in a neonatal intensive care unit. Methods: We conducted a prospective study of continuous video-EEG...
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| Format: | Article |
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MDPI AG
2022-02-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/2/238 |
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| author | Oi-Wa Chan Wan-Hsuan Chen Jainn-Jim Lin Ming-Chou Chiang Shao-Hsuan Hsia Huei-Shyong Wang En-Pei Lee Yi-Shan Wang Cheng-Yen Kuo Kuang-Lin Lin iCNS Group |
| author_facet | Oi-Wa Chan Wan-Hsuan Chen Jainn-Jim Lin Ming-Chou Chiang Shao-Hsuan Hsia Huei-Shyong Wang En-Pei Lee Yi-Shan Wang Cheng-Yen Kuo Kuang-Lin Lin iCNS Group |
| author_sort | Oi-Wa Chan |
| collection | DOAJ |
| description | Background: In general clinical practice, neonatal seizures are identified visually by direct clinical observation. The study aimed to examine the frequency of clinical seizures in paroxysmal events in a neonatal intensive care unit. Methods: We conducted a prospective study of continuous video-EEG monitoring in a neonatal intensive care unit between January 2017 and December 2020. The demographic data were also reviewed. Results: Sixty-four neonates were enrolled. The median total video-EEG monitoring duration was 24.1 h (IQR 17.5–44.8 h). There were 309 clinically suspected seizure episodes, of which 181 (58.6%) were the motor type and 128 (41.4%) were the non-motor type. Only 63 (20.4%) of these events were confirmed to be clinical seizures on a simultaneous video-EEG recording. In terms of the impact of continuous video-EEG monitoring on clinical management, the anti-epileptic drugs were changed in 42 (65.6%) of the 64 neonates. Conclusion: In the identification of neonatal seizures, a clinical diagnosis by direct observation alone is not enough. The use of continuous video-EEG monitoring plays an important role in the diagnosis of neonatal seizures and in guiding clinical management decisions. |
| first_indexed | 2024-03-09T22:18:06Z |
| format | Article |
| id | doaj.art-4c08e121c14941069f1c1f19026bdd03 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T22:18:06Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-4c08e121c14941069f1c1f19026bdd032023-11-23T19:19:45ZengMDPI AGChildren2227-90672022-02-019223810.3390/children9020238The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care UnitOi-Wa Chan0Wan-Hsuan Chen1Jainn-Jim Lin2Ming-Chou Chiang3Shao-Hsuan Hsia4Huei-Shyong Wang5En-Pei Lee6Yi-Shan Wang7Cheng-Yen Kuo8Kuang-Lin Lin9iCNS Group10Division of Pediatric Critical Care and Pediatric Neurocritical Care Center, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDepartment of Pediatrics, Chiayi Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Chiayi 613, TaiwanDivision of Pediatric Critical Care and Pediatric Neurocritical Care Center, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Neonatology, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Pediatric Critical Care and Pediatric Neurocritical Care Center, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Pediatric Neurology, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Pediatric Critical Care and Pediatric Neurocritical Care Center, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Pediatric Neurology, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Pediatric Neurology, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanDivision of Pediatric Neurology, Chang Gung Children’s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, TaiwanStudy Group for Intensive and Integrated Care of Pediatric Central Nervous System, Chang Gung Children’s Hospital, Taoyuan 333, TaiwanBackground: In general clinical practice, neonatal seizures are identified visually by direct clinical observation. The study aimed to examine the frequency of clinical seizures in paroxysmal events in a neonatal intensive care unit. Methods: We conducted a prospective study of continuous video-EEG monitoring in a neonatal intensive care unit between January 2017 and December 2020. The demographic data were also reviewed. Results: Sixty-four neonates were enrolled. The median total video-EEG monitoring duration was 24.1 h (IQR 17.5–44.8 h). There were 309 clinically suspected seizure episodes, of which 181 (58.6%) were the motor type and 128 (41.4%) were the non-motor type. Only 63 (20.4%) of these events were confirmed to be clinical seizures on a simultaneous video-EEG recording. In terms of the impact of continuous video-EEG monitoring on clinical management, the anti-epileptic drugs were changed in 42 (65.6%) of the 64 neonates. Conclusion: In the identification of neonatal seizures, a clinical diagnosis by direct observation alone is not enough. The use of continuous video-EEG monitoring plays an important role in the diagnosis of neonatal seizures and in guiding clinical management decisions.https://www.mdpi.com/2227-9067/9/2/238frequencyclinical seizureparoxysmal eventsNICU |
| spellingShingle | Oi-Wa Chan Wan-Hsuan Chen Jainn-Jim Lin Ming-Chou Chiang Shao-Hsuan Hsia Huei-Shyong Wang En-Pei Lee Yi-Shan Wang Cheng-Yen Kuo Kuang-Lin Lin iCNS Group The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit Children frequency clinical seizure paroxysmal events NICU |
| title | The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit |
| title_full | The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit |
| title_fullStr | The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit |
| title_full_unstemmed | The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit |
| title_short | The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit |
| title_sort | frequency of clinical seizures in paroxysmal events in a neonatal intensive care unit |
| topic | frequency clinical seizure paroxysmal events NICU |
| url | https://www.mdpi.com/2227-9067/9/2/238 |
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