A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD
Patients with advanced chronic kidney disease (CKD) experience multiple bothersome symptoms, undermining their quality of life (QOL). With growing attention to the importance of symptom management in advanced CKD, the evidence regarding symptoms is increasing. In this review, we briefly summarize th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-04-01
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| Series: | Kidney International Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468024921000711 |
| _version_ | 1818591803822047232 |
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| author | Maureen Metzger Emaad M. Abdel-Rahman Heather Boykin Mi-Kyung Song |
| author_facet | Maureen Metzger Emaad M. Abdel-Rahman Heather Boykin Mi-Kyung Song |
| author_sort | Maureen Metzger |
| collection | DOAJ |
| description | Patients with advanced chronic kidney disease (CKD) experience multiple bothersome symptoms, undermining their quality of life (QOL). With growing attention to the importance of symptom management in advanced CKD, the evidence regarding symptoms is increasing. In this review, we briefly summarize the current evidence of effective pharmacologic and nonpharmacologic interventions to improve symptoms and QOL in patients with advanced CKD, including those on dialysis. We focused on symptoms that are commonly experienced by patients, such as pain, fatigue, sleep disturbances, itching, nausea and vomiting, cognitive impairment, and anxiety and depression. We noted that research in symptom science focused on improving symptom management in CKD is still very limited. In addition to the lack of clinical practice guidelines to address those common symptoms, the major gaps in the current literature include the evidence regarding mechanistic pathways to inform the development of effective symptom management for CKD populations, the evidence to confirm effective pharmacologic interventions in other populations for CKD populations, and research on how to incorporate effective symptom management approaches into clinical care. Although improving mortality remains as an important area in the kidney community, there is an urgent need to focus on improving symptom management to improve QOL in advanced CKD. |
| first_indexed | 2024-12-16T10:18:15Z |
| format | Article |
| id | doaj.art-4c10ef8bfc0240df825e5688e5de77df |
| institution | Directory Open Access Journal |
| issn | 2468-0249 |
| language | English |
| last_indexed | 2024-12-16T10:18:15Z |
| publishDate | 2021-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Kidney International Reports |
| spelling | doaj.art-4c10ef8bfc0240df825e5688e5de77df2022-12-21T22:35:23ZengElsevierKidney International Reports2468-02492021-04-0164894904A Narrative Review of Management Strategies for Common Symptoms in Advanced CKDMaureen Metzger0Emaad M. Abdel-Rahman1Heather Boykin2Mi-Kyung Song3University of Virginia School of Nursing, Charlottesville, Virginia, USADivision of Nephrology, Nephrology, University of Virginia, Charlottesville, Virginia, USAKidney Palliative Care Clinic, University of North Carolina Healthcare, UNC Medical Center, Chapel Hill, North Carolina, USACenter for Nursing Excellence in Palliative Care, Nell Hudgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA; Correspondence: Mi-Kyung Song, Center for Nursing Excellence in Palliative Care, Nell Hudgson Woodruff School of Nursing, Emory University, 1520 Clifton Rd NE, Atlanta, GA 30322.Patients with advanced chronic kidney disease (CKD) experience multiple bothersome symptoms, undermining their quality of life (QOL). With growing attention to the importance of symptom management in advanced CKD, the evidence regarding symptoms is increasing. In this review, we briefly summarize the current evidence of effective pharmacologic and nonpharmacologic interventions to improve symptoms and QOL in patients with advanced CKD, including those on dialysis. We focused on symptoms that are commonly experienced by patients, such as pain, fatigue, sleep disturbances, itching, nausea and vomiting, cognitive impairment, and anxiety and depression. We noted that research in symptom science focused on improving symptom management in CKD is still very limited. In addition to the lack of clinical practice guidelines to address those common symptoms, the major gaps in the current literature include the evidence regarding mechanistic pathways to inform the development of effective symptom management for CKD populations, the evidence to confirm effective pharmacologic interventions in other populations for CKD populations, and research on how to incorporate effective symptom management approaches into clinical care. Although improving mortality remains as an important area in the kidney community, there is an urgent need to focus on improving symptom management to improve QOL in advanced CKD.http://www.sciencedirect.com/science/article/pii/S2468024921000711chronic kidney diseasedialysispalliative carequality of lifesymptom managementsymptoms |
| spellingShingle | Maureen Metzger Emaad M. Abdel-Rahman Heather Boykin Mi-Kyung Song A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD Kidney International Reports chronic kidney disease dialysis palliative care quality of life symptom management symptoms |
| title | A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD |
| title_full | A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD |
| title_fullStr | A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD |
| title_full_unstemmed | A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD |
| title_short | A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD |
| title_sort | narrative review of management strategies for common symptoms in advanced ckd |
| topic | chronic kidney disease dialysis palliative care quality of life symptom management symptoms |
| url | http://www.sciencedirect.com/science/article/pii/S2468024921000711 |
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