A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children
<i>Salmonella</i> is a Gram-negative enteric bacterium responsible for the foodborne and waterborne disease salmonellosis, which is the second most reported bacterial zoonosis in humans. Many animals are potential sources of salmonellosis, including dogs, cats, and other pets. We report...
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MDPI AG
2022-12-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/11/12/1500 |
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| author | Valeria Russini Carlo Corradini Emilia Rasile Giuliana Terracciano Matteo Senese Federica Bellagamba Roberta Amoruso Francesco Bottoni Paola De Santis Stefano Bilei Maria Laura De Marchis Teresa Bossù |
| author_facet | Valeria Russini Carlo Corradini Emilia Rasile Giuliana Terracciano Matteo Senese Federica Bellagamba Roberta Amoruso Francesco Bottoni Paola De Santis Stefano Bilei Maria Laura De Marchis Teresa Bossù |
| author_sort | Valeria Russini |
| collection | DOAJ |
| description | <i>Salmonella</i> is a Gram-negative enteric bacterium responsible for the foodborne and waterborne disease salmonellosis, which is the second most reported bacterial zoonosis in humans. Many animals are potential sources of salmonellosis, including dogs, cats, and other pets. We report the case of an outbreak of salmonellosis in a family in central Italy, affecting two children and involving their three dogs as carriers. One of the children needed medical care and hospitalisation. Isolation and analysis of stool samples from the sibling and the animals present in the house were carried out. Serotyping allowed the identification of <i>S. enterica</i> subsp. <i>enterica</i> serovar Typhimurium in its monophasic variant for all the isolates. The results of whole-genome sequencing confirmed that the strains were tightly related. The minimum inhibitory concentration (MIC) test documented the resistance to ampicillin, sulfamethoxazole, and tetracycline. The origin of the zoonotic outbreak could not be assessed; however, the case study showed a clear passage of the pathogen between the human and non-human members of the family. The possibility of a transmission from a dog to a human suggests the need for further studies on the potential ways of transmission of salmonellosis through standard and alternative feed. |
| first_indexed | 2024-03-09T15:59:15Z |
| format | Article |
| id | doaj.art-4c12a576dd1f4c48b33a841a57cf0da1 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-09T15:59:15Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-4c12a576dd1f4c48b33a841a57cf0da12023-11-24T17:13:47ZengMDPI AGPathogens2076-08172022-12-011112150010.3390/pathogens11121500A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s ChildrenValeria Russini0Carlo Corradini1Emilia Rasile2Giuliana Terracciano3Matteo Senese4Federica Bellagamba5Roberta Amoruso6Francesco Bottoni7Paola De Santis8Stefano Bilei9Maria Laura De Marchis10Teresa Bossù11Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—UOT Toscana Nord, 56123 Pisa, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—UOT Toscana Nord, 56123 Pisa, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—UOT Toscana Nord, 56123 Pisa, ItalyNational Reference Laboratory for Antimicrobial Resistance, General Diagnostics Department, Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”, 00178 Rome, ItalyNational Reference Laboratory for Antimicrobial Resistance, General Diagnostics Department, Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, ItalyIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”—Sezione di Roma, 00178 Rome, Italy<i>Salmonella</i> is a Gram-negative enteric bacterium responsible for the foodborne and waterborne disease salmonellosis, which is the second most reported bacterial zoonosis in humans. Many animals are potential sources of salmonellosis, including dogs, cats, and other pets. We report the case of an outbreak of salmonellosis in a family in central Italy, affecting two children and involving their three dogs as carriers. One of the children needed medical care and hospitalisation. Isolation and analysis of stool samples from the sibling and the animals present in the house were carried out. Serotyping allowed the identification of <i>S. enterica</i> subsp. <i>enterica</i> serovar Typhimurium in its monophasic variant for all the isolates. The results of whole-genome sequencing confirmed that the strains were tightly related. The minimum inhibitory concentration (MIC) test documented the resistance to ampicillin, sulfamethoxazole, and tetracycline. The origin of the zoonotic outbreak could not be assessed; however, the case study showed a clear passage of the pathogen between the human and non-human members of the family. The possibility of a transmission from a dog to a human suggests the need for further studies on the potential ways of transmission of salmonellosis through standard and alternative feed.https://www.mdpi.com/2076-0817/11/12/1500<i>Salmonella</i>One Healthnon-typhoidal <i>Salmonella</i>outbreakST34infants |
| spellingShingle | Valeria Russini Carlo Corradini Emilia Rasile Giuliana Terracciano Matteo Senese Federica Bellagamba Roberta Amoruso Francesco Bottoni Paola De Santis Stefano Bilei Maria Laura De Marchis Teresa Bossù A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children Pathogens <i>Salmonella</i> One Health non-typhoidal <i>Salmonella</i> outbreak ST34 infants |
| title | A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children |
| title_full | A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children |
| title_fullStr | A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children |
| title_full_unstemmed | A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children |
| title_short | A Familiar Outbreak of Monophasic <i>Salmonella</i> serovar Typhimurium (ST34) Involving Three Dogs and Their Owner’s Children |
| title_sort | familiar outbreak of monophasic i salmonella i serovar typhimurium st34 involving three dogs and their owner s children |
| topic | <i>Salmonella</i> One Health non-typhoidal <i>Salmonella</i> outbreak ST34 infants |
| url | https://www.mdpi.com/2076-0817/11/12/1500 |
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