Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus
Human induced pluripotent stem cells (iPSC) resemble human embryonic stem cells with potential to differentiate into cells of all adult tissues. Nonetheless human iPSCs may have an epigenetic memory of their donor tissue origin, are easier to differentiate to those lineages, and their potential to o...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-07-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506122001507 |
| _version_ | 1818552444059123712 |
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| author | Yuanyuan Shi Suihan Wu Bo Yang Baorong Yu Yubo Yan Jiayin Yang Meng Chu Xiaoyu Hu |
| author_facet | Yuanyuan Shi Suihan Wu Bo Yang Baorong Yu Yubo Yan Jiayin Yang Meng Chu Xiaoyu Hu |
| author_sort | Yuanyuan Shi |
| collection | DOAJ |
| description | Human induced pluripotent stem cells (iPSC) resemble human embryonic stem cells with potential to differentiate into cells of all adult tissues. Nonetheless human iPSCs may have an epigenetic memory of their donor tissue origin, are easier to differentiate to those lineages, and their potential to other cell fates can be controlled. We generated a human iPSC line CIBi011-A from amniocytes of a healthy fetus. CIBi011-A serves as a useful source to investigate the epigenetic memory of iPSCs. As an iPSC line from a healthy donor, this line can also serve as a potential cell source from which to develop stem cell-based cell therapies. |
| first_indexed | 2024-12-12T09:13:16Z |
| format | Article |
| id | doaj.art-4c13d79b1d164db98d44dbcdcff6590d |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-12-12T09:13:16Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-4c13d79b1d164db98d44dbcdcff6590d2022-12-22T00:29:27ZengElsevierStem Cell Research1873-50612022-07-0162102801Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetusYuanyuan Shi0Suihan Wu1Bo Yang2Baorong Yu3Yubo Yan4Jiayin Yang5Meng Chu6Xiaoyu Hu7Qingdao Medical College, Qingdao University, Qingdao, Shandong 266021, ChinaDepartment of Obstetrics, Qingdao Municipal Hospital, Qingdao, Shandong 266000, ChinaCell Inspire Biotechnology, Shenzhen, Guangdong 518101, ChinaCell Inspire Biotechnology, Shenzhen, Guangdong 518101, ChinaCell Inspire Biotechnology, Shenzhen, Guangdong 518101, ChinaQingdao Medical College, Qingdao University, Qingdao, Shandong 266021, China; Department of Obstetrics, Qingdao Municipal Hospital, Qingdao, Shandong 266000, China; Cell Inspire Biotechnology, Shenzhen, Guangdong 518101, China; Cell Inspire Therapeutics, Shenzhen, Guangdong 518101, China; Department of Obstetrics, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266000, ChinaCell Inspire Biotechnology, Shenzhen, Guangdong 518101, China; Corresponding authors at: Cell Inspire Biotechnology Co., Ltd., Shenzhen 518101, China (M. Chu). Department of Obstetrics, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266000, China (X. Hu).Department of Obstetrics, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266000, China; Corresponding authors at: Cell Inspire Biotechnology Co., Ltd., Shenzhen 518101, China (M. Chu). Department of Obstetrics, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266000, China (X. Hu).Human induced pluripotent stem cells (iPSC) resemble human embryonic stem cells with potential to differentiate into cells of all adult tissues. Nonetheless human iPSCs may have an epigenetic memory of their donor tissue origin, are easier to differentiate to those lineages, and their potential to other cell fates can be controlled. We generated a human iPSC line CIBi011-A from amniocytes of a healthy fetus. CIBi011-A serves as a useful source to investigate the epigenetic memory of iPSCs. As an iPSC line from a healthy donor, this line can also serve as a potential cell source from which to develop stem cell-based cell therapies.http://www.sciencedirect.com/science/article/pii/S1873506122001507 |
| spellingShingle | Yuanyuan Shi Suihan Wu Bo Yang Baorong Yu Yubo Yan Jiayin Yang Meng Chu Xiaoyu Hu Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus Stem Cell Research |
| title | Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus |
| title_full | Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus |
| title_fullStr | Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus |
| title_full_unstemmed | Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus |
| title_short | Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus |
| title_sort | generation of a human ipsc line cibi011 a from amniocytes of a healthy fetus |
| url | http://www.sciencedirect.com/science/article/pii/S1873506122001507 |
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