New strategies in multiple organ dysfunction syndrometherapy for sepsis
Despite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-directed therapy (EGDT), use of drotrecogin alfa (activated), tight...
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Format: | Article |
Language: | English |
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Serbian Medical Society
2005-01-01
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Series: | Srpski Arhiv za Celokupno Lekarstvo |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2005/0370-81790508379S.pdf |
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author | Šurbatović Maja Radaković Sonja Jovanović Krsta Romić Predrag |
author_facet | Šurbatović Maja Radaković Sonja Jovanović Krsta Romić Predrag |
author_sort | Šurbatović Maja |
collection | DOAJ |
description | Despite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-directed therapy (EGDT), use of drotrecogin alfa (activated), tight control of hyperglycaemia, and adrenal replacement therapy (low doses of corticosteroids)all constitute new treatment strategies. In future, a combination of therapies should be individually adjusted for each patient. |
first_indexed | 2024-12-19T10:38:34Z |
format | Article |
id | doaj.art-4c162d766f154a9490f694a67d067729 |
institution | Directory Open Access Journal |
issn | 0370-8179 |
language | English |
last_indexed | 2024-12-19T10:38:34Z |
publishDate | 2005-01-01 |
publisher | Serbian Medical Society |
record_format | Article |
series | Srpski Arhiv za Celokupno Lekarstvo |
spelling | doaj.art-4c162d766f154a9490f694a67d0677292022-12-21T20:25:31ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792005-01-011337-837938310.2298/SARH0508379SNew strategies in multiple organ dysfunction syndrometherapy for sepsisŠurbatović MajaRadaković SonjaJovanović KrstaRomić PredragDespite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-directed therapy (EGDT), use of drotrecogin alfa (activated), tight control of hyperglycaemia, and adrenal replacement therapy (low doses of corticosteroids)all constitute new treatment strategies. In future, a combination of therapies should be individually adjusted for each patient.http://www.doiserbia.nb.rs/img/doi/0370-8179/2005/0370-81790508379S.pdfsepsisMODSEGDTdrotrecogin |
spellingShingle | Šurbatović Maja Radaković Sonja Jovanović Krsta Romić Predrag New strategies in multiple organ dysfunction syndrometherapy for sepsis Srpski Arhiv za Celokupno Lekarstvo sepsis MODS EGDT drotrecogin |
title | New strategies in multiple organ dysfunction syndrometherapy for sepsis |
title_full | New strategies in multiple organ dysfunction syndrometherapy for sepsis |
title_fullStr | New strategies in multiple organ dysfunction syndrometherapy for sepsis |
title_full_unstemmed | New strategies in multiple organ dysfunction syndrometherapy for sepsis |
title_short | New strategies in multiple organ dysfunction syndrometherapy for sepsis |
title_sort | new strategies in multiple organ dysfunction syndrometherapy for sepsis |
topic | sepsis MODS EGDT drotrecogin |
url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2005/0370-81790508379S.pdf |
work_keys_str_mv | AT surbatovicmaja newstrategiesinmultipleorgandysfunctionsyndrometherapyforsepsis AT radakovicsonja newstrategiesinmultipleorgandysfunctionsyndrometherapyforsepsis AT jovanovickrsta newstrategiesinmultipleorgandysfunctionsyndrometherapyforsepsis AT romicpredrag newstrategiesinmultipleorgandysfunctionsyndrometherapyforsepsis |