The human intermediate prolactin receptor is a mammary proto-oncogene
Abstract The hormone prolactin (PRL) and its receptor (hPRLr) are significantly involved in breast cancer pathogenesis. The intermediate hPRLr (hPRLrI) is an alternatively-spliced isoform, capable of stimulating cellular viability and proliferation. An analogous truncated mouse PRLr (mPRLr) was rece...
Main Authors: | Jacqueline M. Grible, Patricija Zot, Amy L. Olex, Shannon E. Hedrick, J. Chuck Harrell, Alicia E. Woock, Michael O. Idowu, Charles V. Clevenger |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-03-01
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Series: | npj Breast Cancer |
Online Access: | https://doi.org/10.1038/s41523-021-00243-7 |
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