Regenerative Effects of CDP-Choline: A Dose-Dependent Study in the Toxic Cuprizone Model of De- and Remyelination

Regenerative Effects of CDP-Choline: A Dose-Dependent Study in the Toxic Cuprizone Model of De- and Remyelination

Inflammatory attacks and demyelination in the central nervous system (CNS) are the key factors responsible for the damage of neurons in multiple sclerosis (MS). Remyelination is the natural regenerating process after demyelination that also provides neuroprotection but is often incomplete or fails i...

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Bibliographic Details
Main Authors: Viktoria Gudi, Nora Schäfer, Stefan Gingele, Martin Stangel, Thomas Skripuletz
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceuticals
Subjects:
multiple sclerosis
CDP-choline
cuprizone
microglia
astrocytes
oligodendrocytes
Online Access:https://www.mdpi.com/1424-8247/14/11/1156

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