Alteration of the gut microbiome and correlated metabolism in a rat model of long-term depression

Alteration of the gut microbiome and correlated metabolism in a rat model of long-term depression

ObjectiveThis study aims to investigate the composition and function of the gut microbiome in long-term depression using an 8-week chronic unpredictable mild stress (CUMS) rat model.Materials and methodsAnimals were sacrificed after either 4 weeks or 8 weeks under CUMS to mimic long-term depression...

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Bibliographic Details
Main Authors: Yubo Li, Junling Li, Ran Cheng, Haixia Liu, Yukun Zhao, Yanjun Liu, Yanjing Chen, Zhibo Sun, Zhiguang Zhai, Meng Wu, Yupeng Yan, Yuxiu Sun, Zhiguo Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
long-term depression
CUMS
gut microbiome
metabolome
rat
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1116277/full

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