A multidimensional metabolomics workflow to image biodistribution and evaluate pharmacodynamics in adult zebrafish

An integrated evaluation of the tissue distribution and pharmacodynamic properties of a therapeutic is essential for successful translation to the clinic. To date, however, cost-effective methods to measure these parameters at the systems level in model organisms are lacking. Here, we introduce a mu...

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Detaylı Bibliyografya
Asıl Yazarlar: Madelyn M. Jackstadt, Casey A. Chamberlain, Steven R. Doonan, Leah P. Shriver, Gary J. Patti
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: The Company of Biologists 2022-08-01
Seri Bilgileri:Disease Models & Mechanisms
Konular:
Online Erişim:http://dmm.biologists.org/content/15/8/dmm049550