A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics
During the Covid-19 pandemic, the urgent need for safe and effective vaccines has led to many vaccine trials, implying fast and extensive recruitment of volunteers. In France, until 2020, vaccine clinical research participants were usually recruited locally, through center-based pools of volunteers,...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-11-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2022.2109364 |
| _version_ | 1797673156084760576 |
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| author | Marion Bonneton Jessica Sambourg Liem Binh Luong Nguyen Christine Trillou Joyce Dohou Olivier Saint Lary Mathieu Schuers Marie Lachâtre Odile Launay |
| author_facet | Marion Bonneton Jessica Sambourg Liem Binh Luong Nguyen Christine Trillou Joyce Dohou Olivier Saint Lary Mathieu Schuers Marie Lachâtre Odile Launay |
| author_sort | Marion Bonneton |
| collection | DOAJ |
| description | During the Covid-19 pandemic, the urgent need for safe and effective vaccines has led to many vaccine trials, implying fast and extensive recruitment of volunteers. In France, until 2020, vaccine clinical research participants were usually recruited locally, through center-based pools of volunteers, and local communication plans. Covireivac is a French public online platform launched on 10/01/2020 that enables national, large-scale recruitment of volunteers for Covid-19 vaccine studies. On the Covireivac website, all adult participants registered online, gave their informed consent, and filled out two online forms with information on their identity, health status (comorbidities, treatments), and known exposure to SARS-CoV-2. Since July 2021, volunteers could mention if their children are interested in participating in a Covid-19 vaccine trial. The objective of this work is to describe Covireivac’s volunteer characteristics registered from 10/01/2020 to 11/02/2022. To identify independent volunteer characteristics associated with a period of registration we performed a multivariate logistic regression. Among 54,424 registrations, 52,391 (96%) were analysed; 61% were male (n = 31,893), median age was 50 y; 13% (n = 6586) were healthcare workers. At registration, 15,879 volunteers (33%) reported at least one comorbidity, among whom 16% (n = 7349) were obese and 17% (n = 8346) had hypertension. Most volunteers registered during the first month (n = 35,876, 66%). The Covireivac platform allowed quick and large recruitment of potential volunteers for Covid-19 vaccine trials and could be used on a larger scale for vaccine trials in France. It could facilitate recruitment in vaccine trials and provide sponsors with better visibility of the recruitment capacities of clinical research centers. |
| first_indexed | 2024-03-11T21:40:34Z |
| format | Article |
| id | doaj.art-4c2196bb4cdd4f218515e4eec3d1ec73 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:40:34Z |
| publishDate | 2022-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-4c2196bb4cdd4f218515e4eec3d1ec732023-09-26T13:19:08ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-11-0118610.1080/21645515.2022.21093642109364A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristicsMarion Bonneton0Jessica Sambourg1Liem Binh Luong Nguyen2Christine Trillou3Joyce Dohou4Olivier Saint Lary5Mathieu Schuers6Marie Lachâtre7Odile Launay8Hôpital Cochin, Assistance Publique Hôpitaux de ParisHôpital Cochin, Assistance Publique Hôpitaux de ParisHôpital Cochin, Assistance Publique Hôpitaux de ParisFrench Clinical Research Infrastructure Network (F-CRIN)French Clinical Research Infrastructure Network (F-CRIN)Collège National des Enseignants en Médecine GénéraleCollège National des Enseignants en Médecine GénéraleHôpital Cochin, Assistance Publique Hôpitaux de ParisHôpital Cochin, Assistance Publique Hôpitaux de ParisDuring the Covid-19 pandemic, the urgent need for safe and effective vaccines has led to many vaccine trials, implying fast and extensive recruitment of volunteers. In France, until 2020, vaccine clinical research participants were usually recruited locally, through center-based pools of volunteers, and local communication plans. Covireivac is a French public online platform launched on 10/01/2020 that enables national, large-scale recruitment of volunteers for Covid-19 vaccine studies. On the Covireivac website, all adult participants registered online, gave their informed consent, and filled out two online forms with information on their identity, health status (comorbidities, treatments), and known exposure to SARS-CoV-2. Since July 2021, volunteers could mention if their children are interested in participating in a Covid-19 vaccine trial. The objective of this work is to describe Covireivac’s volunteer characteristics registered from 10/01/2020 to 11/02/2022. To identify independent volunteer characteristics associated with a period of registration we performed a multivariate logistic regression. Among 54,424 registrations, 52,391 (96%) were analysed; 61% were male (n = 31,893), median age was 50 y; 13% (n = 6586) were healthcare workers. At registration, 15,879 volunteers (33%) reported at least one comorbidity, among whom 16% (n = 7349) were obese and 17% (n = 8346) had hypertension. Most volunteers registered during the first month (n = 35,876, 66%). The Covireivac platform allowed quick and large recruitment of potential volunteers for Covid-19 vaccine trials and could be used on a larger scale for vaccine trials in France. It could facilitate recruitment in vaccine trials and provide sponsors with better visibility of the recruitment capacities of clinical research centers.http://dx.doi.org/10.1080/21645515.2022.2109364vaccinecovid-19patient selectionclinical trial |
| spellingShingle | Marion Bonneton Jessica Sambourg Liem Binh Luong Nguyen Christine Trillou Joyce Dohou Olivier Saint Lary Mathieu Schuers Marie Lachâtre Odile Launay A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics Human Vaccines & Immunotherapeutics vaccine covid-19 patient selection clinical trial |
| title | A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics |
| title_full | A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics |
| title_fullStr | A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics |
| title_full_unstemmed | A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics |
| title_short | A national platform for Covid-19 vaccine studies recruitment in France: Covireivac volunteer’s characteristics |
| title_sort | national platform for covid 19 vaccine studies recruitment in france covireivac volunteer s characteristics |
| topic | vaccine covid-19 patient selection clinical trial |
| url | http://dx.doi.org/10.1080/21645515.2022.2109364 |
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