Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges
We report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested for hemolytic, hemagglutinating, antibacteria...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-04-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/8/5/1550/ |
| _version_ | 1817992425812000768 |
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| author | Tom Turk Dietrich Mebs Silke Kauferstein Kristina Sepčić |
| author_facet | Tom Turk Dietrich Mebs Silke Kauferstein Kristina Sepčić |
| author_sort | Tom Turk |
| collection | DOAJ |
| description | We report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested for hemolytic, hemagglutinating, antibacterial and anti-acetylcholinesterase (AChE) activities, as well as their ability to inhibit or activate cell protein phosphatase 1 (PP1). The most interesting activities were obtained from extracts of Ircinia felix, Pandaros acanthifolium, Topsentia ophiraphidites, Verongula rigida and Neofibularia nolitangere. Aqueous and organic extracts of I. felix and V. rigida showed strong antibacterial activity. Topsentia aqueous and some organic extracts were strongly hemolytic, as were all organic extracts from I. felix. The strongest hemolytic activity was observed in aqueous extracts from P. acanthifolium. Organic extracts of N. nolitangere and I. felix inhibited PP1. The aqueous extract from Myrmekioderma styx possessed the strongest hemagglutinating activity, whilst AChE inhibiting activity was found only in a few sponges and was generally weak, except in the methanolic extract of T. ophiraphidites. |
| first_indexed | 2024-04-14T01:26:09Z |
| format | Article |
| id | doaj.art-4c22099302b5406b90265049e12914a5 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-14T01:26:09Z |
| publishDate | 2010-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-4c22099302b5406b90265049e12914a52022-12-22T02:20:25ZengMDPI AGMarine Drugs1660-33972010-04-01851550156610.3390/md8051550Biological Activities of Aqueous and Organic Extracts from Tropical Marine SpongesTom TurkDietrich MebsSilke KaufersteinKristina SepčićWe report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested for hemolytic, hemagglutinating, antibacterial and anti-acetylcholinesterase (AChE) activities, as well as their ability to inhibit or activate cell protein phosphatase 1 (PP1). The most interesting activities were obtained from extracts of Ircinia felix, Pandaros acanthifolium, Topsentia ophiraphidites, Verongula rigida and Neofibularia nolitangere. Aqueous and organic extracts of I. felix and V. rigida showed strong antibacterial activity. Topsentia aqueous and some organic extracts were strongly hemolytic, as were all organic extracts from I. felix. The strongest hemolytic activity was observed in aqueous extracts from P. acanthifolium. Organic extracts of N. nolitangere and I. felix inhibited PP1. The aqueous extract from Myrmekioderma styx possessed the strongest hemagglutinating activity, whilst AChE inhibiting activity was found only in a few sponges and was generally weak, except in the methanolic extract of T. ophiraphidites.http://www.mdpi.com/1660-3397/8/5/1550/tropical marine spongeshemolysishemagglutinationantibacterial activityacetylcholinesterase (AChE) inhibitionprotein phosphatase 1 (PP1) inhibition/activation |
| spellingShingle | Tom Turk Dietrich Mebs Silke Kauferstein Kristina Sepčić Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges Marine Drugs tropical marine sponges hemolysis hemagglutination antibacterial activity acetylcholinesterase (AChE) inhibition protein phosphatase 1 (PP1) inhibition/activation |
| title | Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges |
| title_full | Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges |
| title_fullStr | Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges |
| title_full_unstemmed | Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges |
| title_short | Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges |
| title_sort | biological activities of aqueous and organic extracts from tropical marine sponges |
| topic | tropical marine sponges hemolysis hemagglutination antibacterial activity acetylcholinesterase (AChE) inhibition protein phosphatase 1 (PP1) inhibition/activation |
| url | http://www.mdpi.com/1660-3397/8/5/1550/ |
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