Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report)
We investigated the efficacy of danazol treatment in eight patients with HTLV-l associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 patients. The improvement was noted within 15 d...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
1992-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1992000300025&lng=en&tlng=en |
| _version_ | 1818423026992021504 |
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| author | Ailton Melo Luciana Moura Ana Meireles Gerçonita Costa |
| author_facet | Ailton Melo Luciana Moura Ana Meireles Gerçonita Costa |
| author_sort | Ailton Melo |
| collection | DOAJ |
| description | We investigated the efficacy of danazol treatment in eight patients with HTLV-l associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 patients. The improvement was noted within 15 days of danazol administration. Analysis of factors of relevance to the clinical improvement with danazol showed that the beneficial response was preferentially found in females. |
| first_indexed | 2024-12-14T13:35:37Z |
| format | Article |
| id | doaj.art-4c236a7fff8e41968259016cbfd18e90 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-14T13:35:37Z |
| publishDate | 1992-09-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-4c236a7fff8e41968259016cbfd18e902022-12-21T22:59:36ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42271992-09-0150340240310.1590/S0004-282X1992000300025S0004-282X1992000300025Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report)Ailton Melo0Luciana Moura1Ana Meireles2Gerçonita Costa3Universidade Federal da BahiaUniversidade Federal da BahiaUniversidade Federal da BahiaUniversidade Federal da BahiaWe investigated the efficacy of danazol treatment in eight patients with HTLV-l associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 patients. The improvement was noted within 15 days of danazol administration. Analysis of factors of relevance to the clinical improvement with danazol showed that the beneficial response was preferentially found in females.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1992000300025&lng=en&tlng=enparaparesia espástica tropicalHTLV-1mielopatiadanazoltratamento da HAM |
| spellingShingle | Ailton Melo Luciana Moura Ana Meireles Gerçonita Costa Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report) Arquivos de Neuro-Psiquiatria paraparesia espástica tropical HTLV-1 mielopatia danazol tratamento da HAM |
| title | Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report) |
| title_full | Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report) |
| title_fullStr | Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report) |
| title_full_unstemmed | Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report) |
| title_short | Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report) |
| title_sort | danazol a new perspective in the treatment of htlv l associated myelopathy preliminary report |
| topic | paraparesia espástica tropical HTLV-1 mielopatia danazol tratamento da HAM |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1992000300025&lng=en&tlng=en |
| work_keys_str_mv | AT ailtonmelo danazolanewperspectiveinthetreatmentofhtlvlassociatedmyelopathypreliminaryreport AT lucianamoura danazolanewperspectiveinthetreatmentofhtlvlassociatedmyelopathypreliminaryreport AT anameireles danazolanewperspectiveinthetreatmentofhtlvlassociatedmyelopathypreliminaryreport AT gerconitacosta danazolanewperspectiveinthetreatmentofhtlvlassociatedmyelopathypreliminaryreport |