Design, Synthesis and Biological Evaluation of New Pyrimidine Derivatives as Anticancer Agents
Background: Anticancer drug resistance is a challenging phenomenon of growing concern which arises from alteration in drug targets. Despite the fast speed of new chemotherapeutic agent design, the increasing prevalence of this phenomenon requires further research and treatment development. Recently,...
Main Authors: | Valentina Noemi Madia, Alice Nicolai, Antonella Messore, Alessandro De Leo, Davide Ialongo, Valeria Tudino, Francesco Saccoliti, Daniela De Vita, Luigi Scipione, Marco Artico, Samanta Taurone, Ludovica Taglieri, Roberto Di Santo, Susanna Scarpa, Roberta Costi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/3/771 |
Similar Items
-
Pyrrolyl and Indolyl α-γ-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII
by: Davide Ialongo, et al.
Published: (2023-01-01) -
Anti-Tumoral Effects of a (1<i>H</i>-Pyrrol-1-yl)Methyl-1<i>H</i>-Benzoimidazole Carbamate Ester Derivative on Head and Neck Squamous Carcinoma Cell Lines
by: Alice Nicolai, et al.
Published: (2021-06-01) -
Investigating acquired temozolomide resistance in adult glioblastoma
by: Wong, ZY
Published: (2020) -
Design, synthesis and antiproliferative evaluation of lipidated 1,3-diaryl propenones and their cyclized pyrimidine derivatives as tubulin polymerization inhibitors
by: Fatma Elzahraa Ali, et al.
Published: (2023-12-01) -
The multifaceted role of long non-coding RNA DLEU1 in cancer progression: implications for diagnosis and therapy
by: Paweł Stanicki, et al.
Published: (2024-09-01)